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Audrey L. Butler
Researcher at Ragon Institute of MGH, MIT and Harvard
Publications - 7
Citations - 315
Audrey L. Butler is an academic researcher from Ragon Institute of MGH, MIT and Harvard. The author has contributed to research in topics: Immune system & Antibody. The author has an hindex of 4, co-authored 5 publications receiving 126 citations.
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Sex differences in vaccine-induced humoral immunity.
TL;DR: The importance of sex-dependent differences in vaccine-induced immunity is highlighted and the role of sex as a modulator of humoral immunity, key to long-term pathogen-specific protection is addressed.
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A sample-sparing multiplexed ADCP assay
TL;DR: An approach to interrogate the functional activity of antibodies in serum against up to 5 antigen targets simultaneously is described, showing multiplexing allows for accurate and more efficient analysis of antibody-mediated effector profiles.
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Neonate-omics: Charting the Unknown Immune Response in Early Life.
TL;DR: It is shown that newborn immunity varies widely but converges over the first 3 months of life, during this important time window, environmental and genetic factors impact the infant immune system and can influence lifelong immunity.
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The Antibodiome—Mapping the Humoral Immune Response to HIV
TL;DR: Emerging data illustrate a role for innate immune recruiting-antibodies in conferring protection against HIV infection as well as promoting viral control and clearance, offering an unprecedented opportunity to modulate and improve antibody function to fight HIV more effectively.
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Altered maternal antibody profiles in women with HIV drive changes in transplacental antibody transfer.
Sepideh Dolatshahi,Audrey L. Butler,Mark J. Siedner,Joseph Ngonzi,Andrea G. Edlow,Julian Adong,Madeleine F. Jennewein,C. Atyeo,Ingrid V. Bassett,Drucilla J. Roberts,Douglas A. Lauffenburger,Galit Alter,Lisa M. Bebell +12 more
TL;DR: Preserved placental antibody transfer and perturbed immune-dominance profiles in WHIV shift the balance of immunity delivered to neonates, pointing to HIV-associated changes in maternal antibody profiles as a key determinant of compromised neonatal immunity.