Ingrid V. Bassett

TL;DR: A framework for the assessment of point-of-care tests is proposed, and the term test efficacy is suggested to describe the ability of a diagnostic test to support a clinical decision within its operational context, and revised criteria for an ideal diagnostic point- of-care test in resource-limited settings are proposed.

TL;DR: For example, this article found that children may be a potential source of contagion in the SARS-CoV-2 pandemic despite having milder disease or a lack of symptoms; immune dysregulation is implicated in severe postinfectious MIS-C.

TL;DR: Nearly half of HIV-infected persons at two high prevalence sites in Durban, South Africa, failed to have CD4 counts following HIV diagnosis, highlighting the urgent need to improve rates of linkage to HIV care after an initial positive HIV test.

TL;DR: CD4 counts at presentation to care and at ART initiation in sub-Saharan Africa have not increased over the past decade, and barriers to presentation, diagnosis, and linkage to HIV care remain major challenges that require attention.

TL;DR: Loss to care and death occur frequently before starting antiretroviral therapy (ART) among ART eligible HIV-infected patients in Durban, South Africa, and this delay from CD4 count to ART training, even among those with the lowest CD4 counts, highlights the need for interventions that improve linkage to Care and prioritize ART initiation for those with low baselineCD4 counts.