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Audrey M. Neyrinck
Researcher at Université catholique de Louvain
Publications - 162
Citations - 26265
Audrey M. Neyrinck is an academic researcher from Université catholique de Louvain. The author has contributed to research in topics: Gut flora & Prebiotic. The author has an hindex of 49, co-authored 148 publications receiving 21998 citations. Previous affiliations of Audrey M. Neyrinck include Catholic University of Leuven.
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Journal ArticleDOI
Metabolic endotoxemia initiates obesity and insulin resistance
Patrice D. Cani,Jacques Amar,Miguel A. Iglesias,Marjorie Poggi,Claude Knauf,Delphine Bastelica,Audrey M. Neyrinck,Francesca Fava,Kieran Tuohy,Chantal Chabo,Aurélie Waget,Evelyne Delmée,Béatrice Cousin,Thierry Sulpice,Bernard Chamontin,Jean Ferrières,Jean-François Tanti,Glenn R. Gibson,Louis Casteilla,Nathalie M. Delzenne,Marie-Christine Alessi,Rémy Burcelin +21 more
TL;DR: It is concluded that the LPS/CD14 system sets the tone of insulin sensitivity and the onset of diabetes and obesity and lowering plasma LPS concentration could be a potent strategy for the control of metabolic diseases.
Journal ArticleDOI
Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice
Patrice D. Cani,Rodrigo Bibiloni,Claude Knauf,Aurélie Waget,Audrey M. Neyrinck,Nathalie M. Delzenne,Rémy Burcelin +6 more
TL;DR: It is found that changes of gut microbiota induced by an antibiotic treatment reduced metabolic endotoxemia and the cecal content of LPS in both high-fat–fed and ob/ob mice, demonstrating that changes in gut microbiota controls metabolic endotoxinemia, inflammation, and associated disorders by a mechanism that could increase intestinal permeability.
Journal ArticleDOI
Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement of gut permeability
Patrice D. Cani,Sam Possemiers,T. Van de Wiele,Yves Guiot,Amandine Everard,O. Rottier,Lucie Geurts,Damien Naslain,Audrey M. Neyrinck,Didier M. Lambert,Giulio G. Muccioli,Nathalie M. Delzenne +11 more
TL;DR: It is found that a selective gut microbiota change controls and increases endogenous GLP-2 production, and consequently improves gut barrier functions by a GLP1-2-dependent mechanism, contributing to the improvement of Gut barrier functions during obesity and diabetes.
Journal ArticleDOI
Prebiotic effects: metabolic and health benefits.
Marcel Roberfroid,Glenn R. Gibson,Lesley Hoyles,Anne L. McCartney,Robert A. Rastall,Ian Rowland,Danielle Wolvers,Bernhard Watzl,Hania Szajewska,Bernd Stahl,Francisco Guarner,Frédérique Respondek,Kevin Whelan,Véronique Coxam,Marie-Jeanne Davicco,Laurent Léotoing,Yohann Wittrant,Nathalie M. Delzenne,Patrice D. Cani,Audrey M. Neyrinck,Agnes Meheust +20 more
TL;DR: The present document has been written by a group of both academic and industry experts and aims to validate and expand the original idea of the prebiotic concept, defined as the selective stimulation of growth and/or activity of one or a limited number of microbial genus(era)/species in the gut microbiota that confer(s) health benefits to the host.
Journal ArticleDOI
Selective increases of bifidobacteria in gut microflora improve high-fat-diet-induced diabetes in mice through a mechanism associated with endotoxaemia.
Patrice D. Cani,Audrey M. Neyrinck,Francesca Fava,Claude Knauf,Rémy Burcelin,Kieran Tuohy,Glenn R. Gibson,Nathalie M. Delzenne,Nathalie M. Delzenne +8 more
TL;DR: The findings suggest that the gut microbiota contribute towards the pathophysiological regulation of endotoxaemia and set the tone of inflammation for occurrence of diabetes and/or obesity.