Ausra Bendoraite

TL;DR: The data indicate that hESC express a larger complement of miRNAs than previously appreciated, and they provide a resource for additional studies of miRNA regulation of h ESC physiology.

TL;DR: Analysis of ovarian cancer tissues suggests that ovarian surface cells acquire a more epithelial miR-200-ZEB1/2 phenotype as they undergo transformation, suggesting the mesothelial-to-epithelial (Meso-E-T) model for development of ovarian cancers that arise from ovariansurface cells, as has been proposed previously on the basis of studies of protein markers.

TL;DR: Canine embryonic stem cell lines were generated to establish a large‐animal preclinical model for testing the safety and efficacy of embryonic stem (ES) cell‐derived tissue replacement therapy and one line, Fred Hutchinson dog (FHDO)‐7, has been maintained through 34 passages and is presented here.

TL;DR: A universal reference microRNA reagent set as well as a series of nonhuman spiked-in synthetic microRNA controls are introduced, and their use for quality control and between-array normalization of microRNA expression data is demonstrated.

TL;DR: Results indicate that FHDO-7 is a pluripotent embryonic stem cell line.