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Walter L. Ruzzo

Researcher at University of Washington

Publications -  121
Citations -  13923

Walter L. Ruzzo is an academic researcher from University of Washington. The author has contributed to research in topics: Gene & RNA. The author has an hindex of 47, co-authored 120 publications receiving 13133 citations. Previous affiliations of Walter L. Ruzzo include J. Craig Venter Institute & Seattle University.

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Journal ArticleDOI

Protection in operating systems

TL;DR: A model of protection mechanisms in computing systems is presented and its appropriateness is argued and it can be shown that this problem is decidable, i.e. there is an algorithm to determine whether a system in a particular configuration is safe.
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Principal component analysis for clustering gene expression data.

TL;DR: The empirical study showed that clustering with the PCs instead of the original variables does not necessarily improve, and often degrades, cluster quality, and would not recommend PCA before clustering except in special circumstances.
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Model-based clustering and data transformations for gene expression data.

TL;DR: The model-based approach has superior performance on synthetic data sets, consistently selecting the correct model and the number of clusters, and the validity of the Gaussian mixture assumption on different transformations of real data is explored.
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Validating clustering for gene expression data

TL;DR: This work provides a systematic framework for assessing the results of clustering algorithms for gene expression data sets by applying a clustering algorithm to the data from all but one experimental condition.