B
B S Stein
Researcher at Stanford University
Publications - 11
Citations - 1814
B S Stein is an academic researcher from Stanford University. The author has contributed to research in topics: Virus & T cell. The author has an hindex of 10, co-authored 11 publications receiving 1798 citations. Previous affiliations of B S Stein include Gulf Coast Regional Blood Center & Veterans Health Administration.
Papers
More filters
Journal ArticleDOI
pH-independent HIV entry into CD4-positive T cells via virus envelope fusion to the plasma membrane
B S Stein,B S Stein,S D Gowda,S D Gowda,Jeffrey D. Lifson,Jeffrey D. Lifson,Jeffrey D. Lifson,Robert C. Penhallow,Klaus G. Bensch,Edgar G. Engleman,Edgar G. Engleman,Edgar G. Engleman +11 more
TL;DR: It is indicated that HIV penetrates CD4-positive T cells via pH-independent membrane fusion through direct fusion of the virus envelope with the plasma membrane within minutes at 4 degrees C.
Journal ArticleDOI
AIDS retrovirus induced cytopathology: giant cell formation and involvement of CD4 antigen
Jeffrey D. Lifson,Jeffrey D. Lifson,Gregory R. Reyes,Michael S. McGrath,B S Stein,B S Stein,Edgar G. Engleman,Edgar G. Engleman +7 more
TL;DR: It is suggested that, in vivo, cell fusion involving the CD4 molecule may represent a mechanism whereby uninfected cells can be incorporated into AIDS virus infected syncytia.
Journal ArticleDOI
Intracellular processing of the gp160 HIV-1 envelope precursor. Endoproteolytic cleavage occurs in a cis or medial compartment of the Golgi complex
B S Stein,Edgar G. Engleman +1 more
TL;DR: Evidence is presented that gp160 is subject to mannose trimming in the Golgi complex, which is inhibited by 1-deoxymannojirimycin (a specific Golgi alpha-mannosidase I inhibitor), and preliminary data suggest that gp120 is post-translationally modified by sialylated O-linked oligosaccharides.
Journal Article
Evidence that T cell activation is required for HIV-1 entry in CD4+ lymphocytes.
TL;DR: Results provide evidence that HIV entry and HIV envelope-dependent cell-to-cell fusion require T cell activation and are a consequence of allogeneic stimulation by the HXB/gpt cell line.
Journal ArticleDOI
Complete inhibition of transferrin recycling by monensin in K562 cells.
B S Stein,K G Bensch,H H Sussman +2 more
TL;DR: Cell-surface-binding sites for transferrin were reduced by 50% with 10(-5) M monensin treatment; however, this effect was not attenuated by 80% protein synthesis inhibition with cycloheximide, supporting the idea that the transferrin receptor is also recycled through the Golgi.