B
Badia Ferzaz
Researcher at University of Bordeaux
Publications - 17
Citations - 1130
Badia Ferzaz is an academic researcher from University of Bordeaux. The author has contributed to research in topics: Ifenprodil & Schwann cell. The author has an hindex of 8, co-authored 17 publications receiving 1104 citations. Previous affiliations of Badia Ferzaz include Sanofi S.A..
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Journal ArticleDOI
Progesterone synthesis and myelin formation by Schwann cells
H. Koenig,Michael Schumacher,Badia Ferzaz,Anh N. Do Thi,Annie Ressouches,Rachida Guennoun,Ingrid Jung-Testas,Paul Robel,Yvette Akwa,Etienne-Emile Baulieu,Etienne-Emile Baulieu +10 more
TL;DR: It is demonstrated that progesterone is not simply a sex steroid, and a new therapeutic approach is suggested to promote myelin repair in male mice after cryolesion of the sciatic nerve.
Journal ArticleDOI
Progesterone Synthesis and Myelin Formation by Schwann Cells
H. Koenig,Michael Schumacher,Badia Ferzaz,Anh N. Do Thi,Annie Ressouches,Rachida Guennoun,Ingrid Jung-Testas,Paul Robel,Yvette Akwa,Etienne-Emile Baulieu +9 more
TL;DR: It is demonstrated that progesterone is not simply a sex steroid, and a new therapeutic approach is suggested to promote myelin repair in male mice after cryolesion of the sciatic nerve.
Journal ArticleDOI
Progesterone synthesis and myelin formation in peripheral nerves
Michael Schumacher,Rachida Guennoun,Gilles Mercier,Franck Desarnaud,Pascale N. Lacor,Jesus Benavides,Badia Ferzaz,Françoise Robert,Etienne-Emile Baulieu +8 more
TL;DR: It has been proposed that progesterone may indirectly regulate myelin formation by influencing gene expression in neurons as well as activating the expression of genes coding for transcription factors and/or for myelin proteins.
Journal ArticleDOI
SSR180575 (7-Chloro-N,N,5-trimethyl-4-oxo-3-phenyl-3,5-dihydro-4H-pyridazino[4,5-b]indole-1-acetamide), a Peripheral Benzodiazepine Receptor Ligand, Promotes Neuronal Survival and Repair
Badia Ferzaz,Emmanuel Brault,Genevieve Bourliaud,Jean-Pierre Robert,Gilles Poughon,Y. Claustre,Franck Marguet,Philippe Liere,Michael Schumacher,Jean-Pierre Nowicki,Jacqueline Fournier,Benoit Marabout,Mireille Sevrin,Pascal George,Philippe Soubrie,Jesus Benavides,Bernard Scatton +16 more
TL;DR: The results indicate that PBR ligands (e.g., SSR180575) promote neuronal survival and repair in axotomy and neuropathy models and have potential for the treatment of neurodegenerative diseases.
Journal ArticleDOI
Regulation of the expression of peripheral benzodiazepine receptors and their endogenous ligands during rat sciatic nerve degeneration and regeneration: a role for PBR in neurosteroidogenesis
Pascale N. Lacor,Pierrick Gandolfo,Marie-Christine Tonon,Emmanuel Brault,Isabelle Dalibert,Michael Schumacher,Jesus Benavides,Badia Ferzaz +7 more
TL;DR: A role for PBR and their endogenous ligands in peripheral nerve regeneration could be exerted via stimulation of steroid synthesis, and the greater accumulation of intermediate forms when regeneration is allowed to occur may indicate a particular role of these forms in axonal elongation and myelination.