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Balaraman Kalyanaraman

Researcher at Medical College of Wisconsin

Publications -  488
Citations -  42413

Balaraman Kalyanaraman is an academic researcher from Medical College of Wisconsin. The author has contributed to research in topics: Radical & Superoxide. The author has an hindex of 100, co-authored 475 publications receiving 38562 citations. Previous affiliations of Balaraman Kalyanaraman include University of Alabama at Birmingham & University of Alabama.

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Reactions of Nitric Oxide with Nitronyl Nitroxides and Oxygen: Prediction of Nitrite and Nitrate Formation by Kinetic Simulation

TL;DR: The model agrees with previous experimental observations that the aqueous oxidation of .NO in air saturated solutions will exclusively form nitrite and predicts that .NO will only generate substantial amounts of nitrate if it is released at a rate less than 10(-17) M/s.
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Rapid-onset endothelial dysfunction with adriamycin: evidence for a dysfunctional nitric oxide synthase.

TL;DR: ADR administration results in rapid depletion of systemic NO· levels and attenuation of agonist-dependent responses in rabbits and flow-mediated dilation in the brachial artery of humans.
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Synergistic interaction between the probucol phenoxyl radical and ascorbic acid in inhibiting the oxidation of low density lipoprotein.

TL;DR: The reaction between the phenoxyl radical of probucol and ascorbate results in a synergistic enhancement of the antioxidant capacity of these two compounds and it is speculated that such reactions could play a role in maintaining the antioxidant status of LDL during oxidative stress in vivo.
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Nitration and oxidation of a hydrophobic tyrosine probe by peroxynitrite in membranes: comparison with nitration and oxidation of tyrosine by peroxynitrite in aqueous solution.

TL;DR: It is concluded that nitration but not oxidation of a tyrosyl probe by peroxynitrite is a predominant reaction in the membrane, and the local environment of target tyrosine residues is an important factor governing its propensity to undergo nitration in the presence of peroxlynitrite.
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Production of singlet oxygen-derived hydroxyl radical adducts during merocyanine-540-mediated photosensitization: analysis by ESR-spin trapping and HPLC with electrochemical detection.

TL;DR: It is proposed that 1O2 reacts with DMPO to give an intermediate which decays to form D MPO/.OH and free, and that the reaction between 1O1 and SA preferentially forms the 2,5-DHBA isomer.