B
Balaraman Kalyanaraman
Researcher at Medical College of Wisconsin
Publications - 488
Citations - 42413
Balaraman Kalyanaraman is an academic researcher from Medical College of Wisconsin. The author has contributed to research in topics: Radical & Superoxide. The author has an hindex of 100, co-authored 475 publications receiving 38562 citations. Previous affiliations of Balaraman Kalyanaraman include University of Alabama at Birmingham & University of Alabama.
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An ESR study of the nitroxide radical of pentastarch-conjugated deferoxamine.
TL;DR: A novel derivative of DFO may provide some additional benefit in limiting DFO nitroxide radical formation and might explain the reported reduced in vivo toxicity of MPS-DFO relative to free DFO.
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Reactive oxygen species induce reversible PECAM-1 tyrosine phosphorylation and SHP-2 binding
Matthias Maas,Ronggang Wang,Cathy Paddock,Srigiridhar Kotamraju,Balaraman Kalyanaraman,Peter J. Newman,Debra K. Newman +6 more
TL;DR: It is shown that PECAM-1 tyrosine phosphorylation in response to exposure of cells to H2O2 is reversible, involves a shift in the balance between kinase and phosphatase activities, and supports binding of SHP-2 and recruitment of this phosphatases to cell-cell borders.
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Mechanism of oxidation of 1-methyl-4-phenyl-2,3-dihydropyridinium (MPDP+).
TL;DR: Oxidase electrode measurements have shown that the neurotoxin metabolite 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine autoxidizes to hydrogen peroxide and 1- methyl- 4- phenylpyridinium in a reaction promoted by iron chelates.
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Embedding cyclic nitrone in mesoporous silica particles for EPR spin trapping of superoxide and other radicals.
Eric Besson,Stéphane Gastaldi,Emily Bloch,Jacek Zielonka,Monika Zielonka,Balaraman Kalyanaraman,Selma Aslan,Hakim Karoui,Antal Rockenbauer,Olivier Ouari,Micael Hardy +10 more
TL;DR: The synthesis and characterization of a new mesoporous silica functionalized with a phosphorylated cyclic spin trap (DIPPMPO nitrone) is reported, enabling the identification of a wide range of carbon or oxygen-centered transient radicals in organic and in aqueous media.
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Spin trapping of nitrogen dioxide radical from photolytic decomposition of nitramines
M.D. Pace,Balaraman Kalyanaraman +1 more
TL;DR: The photochemical decomposition of some monocyclic and polycyclic nitramines produces .NO2, which can be detected in the respective nitramine crystals at 77 K by EPR (electron paramagnetic resonance) and the net growth in spin concentration measured from EPR spectra is fitted by a first-order rate equation.