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Bálint Mészáros

Researcher at Eötvös Loránd University

Publications -  48
Citations -  4005

Bálint Mészáros is an academic researcher from Eötvös Loránd University. The author has contributed to research in topics: Intrinsically disordered proteins & Computer science. The author has an hindex of 19, co-authored 43 publications receiving 2829 citations. Previous affiliations of Bálint Mészáros include Hungarian Academy of Sciences & European Bioinformatics Institute.

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IUPred2A: context-dependent prediction of protein disorder as a function of redox state and protein binding

TL;DR: A combined web interface that allows to generate energy estimation based predictions for ordered and disordered residues by IUPred2 and for disordered binding regions by ANCHOR2 is presented and the updated web server retains the robustness of the original programs but offers several new features.
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ANCHOR: web server for predicting protein binding regions in disordered proteins.

TL;DR: ANCHOR is a web-based implementation of an original method that takes a single amino acid sequence as an input and predicts protein binding regions that are disordered in isolation but can undergo disorder-to-order transition upon binding.
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Prediction of Protein Binding Regions in Disordered Proteins

TL;DR: Scanning several hundred proteomes showed that the occurrence of disordered binding sites increased with the complexity of the organisms even compared to disordered regions in general, and the length distribution of binding sites was different from disordered protein regions ingeneral and was dominated by shorter segments.
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Molecular principles of the interactions of disordered proteins.

TL;DR: The findings provide a structural rationale to the prior suggestions that many IUPs are specialized for functions realized by protein-protein interactions, and help explain the increased evolutionary conservation of IUP interface residues.