B
Barbara Casadei
Researcher at University of Oxford
Publications - 274
Citations - 23925
Barbara Casadei is an academic researcher from University of Oxford. The author has contributed to research in topics: Atrial fibrillation & Medicine. The author has an hindex of 60, co-authored 242 publications receiving 19620 citations. Previous affiliations of Barbara Casadei include Newman University & King's College London.
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Journal Article
A cardiac nitric oxide synthase 1 regulates contraction and calcium fluxes - a novel mechanism in the autocrine control of cardiac function
Euan A. Ashley,Claire E. Sears,Craig A. Lygate,Simon M. Bryant,Helen L. Wallis,Stefan Neubauer,Barbara Casadei +6 more
Journal ArticleDOI
142 Atrial sources of reactive oxygen species vary with the substrate and duration of atrial fibrillation: implications for the antiarrhythmic effect of statins
Svetlana Reilly,Raja Jayaram,C Anroniades,S Verheule,K M Channon,Nicholas J. Alp,Ulrich Schotten,Barbara Casadei +7 more
TL;DR: Findings indicate that upregulation of NOX2-NADPH oxidases is an early but transient event in the natural history of AF, as mitochondrial oxidases and uncoupled NOS account for the statin-resistant increase in atrial superoxide production in permanent AF.
Journal Article
Is depressed myocyte contractility an early event in the natural history of heart failure
Journal ArticleDOI
A Doppler derived index of diastolic function; Independent of preload, heart rate and atrio-ventricular interval
Theo E. Meyer,Barbara Casadei,Alberto Radaelli,Andrew J.S. Coats,Stam Adampoulos,James R.W. Conway,Peter Sleight +6 more
Changes in extracellular pH mediate the chronotropic responses
TL;DR: In vitro, L-Arg can markedly affect HR through a pH-mediated, NO-independent mechanism and the opposing changes in [pH]o induced by different formulations of L- Arg can importantly confound the assessment of the biological effects of this amino acid.