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Barry J. McDonnell

Researcher at Cardiff Metropolitan University

Publications -  87
Citations -  2641

Barry J. McDonnell is an academic researcher from Cardiff Metropolitan University. The author has contributed to research in topics: Blood pressure & Pulse wave velocity. The author has an hindex of 19, co-authored 77 publications receiving 2223 citations. Previous affiliations of Barry J. McDonnell include Cardiff University & RMIT University.

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Central Pressure: Variability and Impact of Cardiovascular Risk Factors: The Anglo-Cardiff Collaborative Trial II

TL;DR: It is demonstrated that cardiovascular risk factors affect the pulse pressure ratio, and that central pressure cannot be reliably inferred from peripheral pressure, and assessment of central pressure may improve the identification and management of patients with elevated cardiovascular risk.
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Endothelial function is associated with pulse pressure, pulse wave velocity, and augmentation index in healthy humans.

TL;DR: In healthy individuals, a decline in endothelial function is associated with increased large artery stiffness, wave reflections, and central pulse pressure, and inversely associated with aortic PWV and augmentation index.
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Increased Stroke Volume and Aortic Stiffness Contribute to Isolated Systolic Hypertension in Young Adults

TL;DR: It is demonstrated that in young adults, isolated systolic hypertension and essential hypertension arise from different hemodynamic mechanisms, whereas the major hemodynamic abnormality underlying essential hypertension is an increased peripheral vascular resistance.
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Aortic Calcification Is Associated With Aortic Stiffness and Isolated Systolic Hypertension in Healthy Individuals

TL;DR: Calcification may underlie treatment resistance in ISH, and anticalcification strategies may present a novel therapy, which suggest that calcification may be important in the process of aortic stiffening and the development of ISH.
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Validation of non-invasive central blood pressure devices: ARTERY Society task force consensus statement on protocol standardization

TL;DR: This article was published in European Heart Journal on 30 January 2017, available open access at https://doi.org/10.1093/eurheartj/ehw632.