Bart Hoorelbeke

TL;DR: The ability of truncated Bid (tBid) to induce the release of a DNAse activity from mitochondria during apoptosis was confirmed in the liver from mice injected with agonistic anti-Fas antibody and is completely prevented in Bcl-2 transgenic mice.

TL;DR: A novel gel-free proteomic technology was used to identify more than 800 proteins from 50 million Escherichia coli K12 cells in a single analysis, demonstrating the high dynamic range and the flexibility in the peptide sorting chemistry.

TL;DR: Proteome maps and a table of all identified proteins have been made available on the world wide web at www.gram.dk.au.

TL;DR: The combination of peptide mass fingerprinting and PSD and analysis described here generally leads to unambiguous protein identification in the amount of material range generally encountered in most proteome studies.

TL;DR: It is demonstrated that a physiologically relevant concentration of tBid is sufficient to induce release of particular intermembrane mitochondrial proteins belonging to a broad molecular-mass range.