K
Kris Gevaert
Researcher at Ghent University
Publications - 476
Citations - 28249
Kris Gevaert is an academic researcher from Ghent University. The author has contributed to research in topics: Proteome & Proteomics. The author has an hindex of 83, co-authored 445 publications receiving 24088 citations. Previous affiliations of Kris Gevaert include Novo Nordisk & Flanders Institute for Biotechnology.
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Journal ArticleDOI
Improved visualization of protein consensus sequences by iceLogo.
Niklaas Colaert,Niklaas Colaert,Kenny Helsens,Kenny Helsens,Lennart Martens,Joël Vandekerckhove,Joël Vandekerckhove,Kris Gevaert,Kris Gevaert +8 more
TL;DR: FASP method is described as “universal” for its ability to represent the proteome in an unbiased way, which was demonstrated by comparison to the transcriptome by demonstrating a disproportionate reduction in peptide ion current, peptide or protein identifications.
Journal ArticleDOI
Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.
Kris Gevaert,Marc Goethals,Lennart Martens,Jozef Van Damme,An Staes,Grégoire Thomas,Joël Vandekerckhove +6 more
TL;DR: A diagonal method to isolate N-terminal peptides from in vivo blocked proteins based on diagonal electrophoresis and diagonal chromatography is described.
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PRIDE: The proteomics identifications database
Lennart Martens,Henning Hermjakob,Philip Jones,Marcin Adamski,Chris F. Taylor,David J. States,Kris Gevaert,Joël Vandekerckhove,Rolf Apweiler +8 more
TL;DR: The proteomics identifications (PRIDE) database is proposed as a means to finally turn publicly available data into publicly accessible data and offers a web‐based query interface, a user‐friendly data upload facility, and a documented application programming interface for direct computational access.
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Proteomics analyses reveal the evolutionary conservation and divergence of N-terminal acetyltransferases from yeast and humans
Thomas Arnesen,Petra Van Damme,Bogdan Polevoda,Kenny Helsens,Rune Evjenth,Niklaas Colaert,Jan Erik Varhaug,Joël Vandekerckhove,Johan R. Lillehaug,Fred Sherman,Kris Gevaert +10 more
TL;DR: Although the COmbined FRActional DIagonal Chromatography technology was used to determine the N-terminal acetylation status of 742 human and yeast protein N termini, it was revealed that NatA from humans and yeast have identical or nearly identical specificities.
Journal ArticleDOI
Global Analysis of the Mitochondrial N-Proteome Identifies a Processing Peptidase Critical for Protein Stability
F-Nora Vögtle,Stefanie Wortelkamp,René P. Zahedi,Dorothea Becker,Dorothea Becker,Claudia Leidhold,Kris Gevaert,Josef Kellermann,Wolfgang Voos,Wolfgang Voos,Albert Sickmann,Nikolaus Pfanner,Chris Meisinger +12 more
TL;DR: This work has identified the intermediate cleaving peptidase ICP55, which removes an amino acid from a characteristic set of MPP-generated N-termini, solving the controversial situation ofMPP specificity and suggesting that Icp55 converts instable intermediates into stable proteins.