B
Bart P.C. van de Warrenburg
Researcher at Radboud University Nijmegen
Publications - 256
Citations - 10535
Bart P.C. van de Warrenburg is an academic researcher from Radboud University Nijmegen. The author has contributed to research in topics: Ataxia & Spinocerebellar ataxia. The author has an hindex of 50, co-authored 231 publications receiving 8226 citations. Previous affiliations of Bart P.C. van de Warrenburg include Radboud University Nijmegen Medical Centre & UCL Institute of Neurology.
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Journal ArticleDOI
Neurological gait disorders in elderly people: clinical approach and classification
TL;DR: A clinically oriented approach to neurological gait disorders in the elderly population is presented and a practical three-step approach to categorise gait Disorders is proposed based on clinical signs and symptoms.
Journal ArticleDOI
Postural deformities in Parkinson's disease
Karen M. Doherty,Bart P.C. van de Warrenburg,Maria Cecilia Peralta,Laura Silveira-Moriyama,Jean-Philippe Azulay,Oscar S. Gershanik,Bastiaan R. Bloem +6 more
TL;DR: Improved understanding of the mechanisms underlying postural deformities in PD might ultimately lead to more effective management strategies for these disabling and drug-refractory complications.
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Mutations in SLC30A10 Cause Parkinsonism and Dystonia with Hypermanganesemia, Polycythemia, and Chronic Liver Disease
Marialuisa Quadri,Antonio Federico,Tianna Zhao,Guido J. Breedveld,Carla Battisti,Cathérine C.S. Delnooz,Lies Anne Severijnen,Lara Di Toro Mammarella,Andrea Mignarri,Lucia Monti,Antioco Sanna,Peng Lu,Francesca Punzo,Francesca Punzo,Giovanni Cossu,Rob Willemsen,Fabrizio Rasi,Ben A. Oostra,Bart P.C. van de Warrenburg,Vincenzo Bonifati +19 more
TL;DR: The SLC30A10 mutations cause a treatable recessive disease with pleomorphic phenotype with broad implications for understanding of the manganese biology and pathophysiology in multiple human organs and compelling evidence that SLC 30A10 plays a pivotal role inManganese transport is provided.
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A post-hoc comparison of the utility of sanger sequencing and exome sequencing for the diagnosis of heterogeneous diseases
Kornelia Neveling,Ilse Feenstra,Christian Gilissen,Lies H. Hoefsloot,Erik-Jan Kamsteeg,Arjen R. Mensenkamp,Richard J. Rodenburg,Helger G. Yntema,Liesbeth Spruijt,Sascha Vermeer,Tuula Rinne,Koen L.I. van Gassen,Danielle Bodmer,Dorien Lugtenberg,Rick de Reuver,Wendy Buijsman,Ronny Derks,Nienke Wieskamp,Bert van den Heuvel,Marjolijn J. L. Ligtenberg,Hannie Kremer,David A. Koolen,Bart P.C. van de Warrenburg,Frans P.M. Cremers,Carlo Marcelis,Jan A.M. Smeitink,Saskia B. Wortmann,Wendy A. G. van Zelst-Stams,Joris A. Veltman,Han G. Brunner,Hans Scheffer,Marcel R. Nelen +31 more
TL;DR: It is found that exome sequencing has a much higher diagnostic yield than Sanger sequencing for deafness, blindness, mitochondrial disease, and movement disorders, and for microsatellite‐stable colorectal cancer, this was low under both strategies.
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How might physical activity benefit patients with Parkinson disease
Arlène D. Speelman,Bart P.C. van de Warrenburg,Marlies van Nimwegen,Giselle M. Petzinger,Marten Munneke,Bastiaan R. Bloem +5 more
TL;DR: Identifying ways to induce a sustained behavioral change, using specifically tailored programs that address potential barriers such as depression, apathy and postural instability, may lead to an improved quality of life in individuals with PD.