K
Karen M. Doherty
Researcher at UCL Institute of Neurology
Publications - 26
Citations - 1285
Karen M. Doherty is an academic researcher from UCL Institute of Neurology. The author has contributed to research in topics: Parkinsonism & Dystonia. The author has an hindex of 13, co-authored 24 publications receiving 1064 citations. Previous affiliations of Karen M. Doherty include University of London & University College London.
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Journal ArticleDOI
Postural deformities in Parkinson's disease
Karen M. Doherty,Bart P.C. van de Warrenburg,Maria Cecilia Peralta,Laura Silveira-Moriyama,Jean-Philippe Azulay,Oscar S. Gershanik,Bastiaan R. Bloem +6 more
TL;DR: Improved understanding of the mechanisms underlying postural deformities in PD might ultimately lead to more effective management strategies for these disabling and drug-refractory complications.
Journal ArticleDOI
Identification of genetic variants associated with Huntington's disease progression: a genome-wide association study
Davina J. Hensman Moss,Antonio F. Pardiñas,Douglas R. Langbehn,Kitty Lo,Blair R. Leavitt,Raymund A.C. Roos,Alexandra Durr,Simon Mead,A. Coleman,R. Dar Santos,J Decolongon,A Sturrock,Eric Bardinet,C Jauff Ret,D Justo,S Lehericy,C Marelli,K. Nigaud,Romain Valabregue,Sja van den Bogaard,E M Dumas,J. van der Grond,EP t'Hart,C Jurgens,M-N Witjes-Ane,N Arran,J Callaghan,C Stopford,Chris Frost,Randi Jones,Nicola Z. Hobbs,N Lahiri,Roger J. Ordidge,Gail Owen,Tracey Pepple,J Read,Miranda J. Say,E Wild,Ameen Patel,Nick C. Fox,C Gibbard,Ian B. Malone,HE Crawford,D Whitehead,S. E. Keenan,David M. Cash,Claire M. Berna,N Bechtel,S Bohlen,A Hoff Man,P H Kraus,Eric Axelson,C Wang,T Acharya,Sang Hong Lee,W Monaco,C Campbell,Sarah Queller,K.B. Whitlock,Meghan C. Campbell,E Frajman,C Milchman,A O'Regan,Izelle Labuschagne,Julie C. Stout,B Landwehrmeyer,D Craufurd,RI Scahill,Stephen Hicks,Christopher Kennard,Hans J. Johnson,Allan J. Tobin,H. D. Rosas,R Reilmann,Beth Borowsky,C Pourchot,Sophie C. Andrews,Anne-Catherine Bachoud-Lévi,Anna Rita Bentivoglio,Ida Biunno,Raphael Bonelli,Jean-Marc Burgunder,Stephen B. Dunnett,Joaquim Ferreira,Olivia Handley,Arvid Heiberg,Torsten Illmann,G. Bernhard Landwehrmeyer,Jamie Levey,Maria A. Ramos-Arroyo,Jorgen E. Nielsen,Susana Pro Koivisto,Markku Päivärinta,R A C Roos,A Rojo Sebastián,Sarah Tabrizi,Wim Vandenberghe,Christine Verellen-Dumoulin,Tereza Uhrová,Jan Wahlström,Jacek Zaremba,Verena Baake,Katrin Barth,Monica Bascuñana Garde,Sabrina Betz,Reineke Bos,Jenny Callaghan,Adrien Come,Leonor Correia Guedes,D. Ecker,Ana Maria Finisterra,Ruth Fullam,Mette Gilling,Lena Gustafsson,Olivia J. Handley,Carina Hvalstedt,Christine Held,Kerstin Koppers,Claudia Lamanna,Matilde Laura,Asunción Martínez Descals,Saul Martinez-Horta,Tiago A. Mestre,Sara Minster,D. Monza,Lisanne Mütze,Martin Oehmen,Michael Orth,Hélène Padieu,Laurent Paterski,Nadia Peppa,Martina Di Renzo,Amandine Rialland,Niini Røren,Pavla Šašinková,Erika Timewell,Jenny Townhill,Patricia Trigo Cubillo,Wildson Vieira da Silva,Marleen R. van Walsem,Carina Whalstedt,Marie-Noëlle W. Witjes-Ané,Grzegorz Witkowski,Abigail Wright,Daniel Zielonka,Eugeniusz Zielonka,Paola Zinzi,Raphael M. Bonelli,Sabine Lilek,Karen Hecht,Brigitte Herranhof,Anna Holl,Hans-Peter Kapfhammer,Michael Koppitz,Markus Magnet,Nicole Müller,Daniela Otti,Annamaria Painold,Karin Reisinger,Monika Scheibl,Helmut Schöggl,Jasmin Ullah,Eva-Maria Braunwarth,Florian Brugger,Lisa Buratti,Eva-Maria Hametner,Caroline Hepperger,Christiane Holas,Anna Hotter,Anna Hussl,Christoph Müller,Werner Poewe,Klaus Seppi,Fabienne Sprenger,Gregor K. Wenning,Andrea Boogaerts,Godelinde Calmeyn,Isabelle Delvaux,Dirk Liessens,Nele Somers,Michel Dupuit,Cécile Minet,Dominique van Paemel,Pascale Ribai,Dimphna van Reijen,Jiri Klempir,Veronika Majerová,Jan Roth,Irena Stárková,Lena E. Hjermind,Oda Jacobsen,Jørgen E. Nielsen,Ida Unmack Larsen,Tua Vinther-Jensen,Heli Hiivola,Hannele Hyppönen,Kirsti Martikainen,Katri Tuuha,Philippe Allain,Dominique Bonneau,Marie Bost,Bénédicte Gohier,Marie-Anne Guérid,Audrey Olivier,Adriana Prundean,Clarisse Scherer-Gagou,Christophe Verny,Blandine Babiloni,Sabrina Debruxelles,Charlotte Duché,Cyril Goizet,Laetitia Jameau,Danielle Lafoucrière,Umberto Spampinato,Rekha Barthélémy,Christelle De Bruycker,Maryline Cabaret Anne-Sophie Carette,Eric Decorte Luc Defebvre,Marie Delliaux,Arnaud Delval,Alain Destée,Kathy Dujardin,Marie-Hélène Lemaire,Sylvie Manouvrier,Mireille Peter,Lucie Plomhouse,Bernard Sablonnière,Clémence Simonin,Stéphanie Thibault-Tanchou,Isabelle Vuillaume,Marcellin Bellonet,Hassan Berrissoul,Stephanie Blin,Françoise Courtin,Cécile Duru,Véronique Fasquel,Olivier Godefroy,Pierre Krystkowiak,Béatrice Mantaux,Martine F. Roussel,Sandrine Wannepain,Jean-Philippe Azulay,Marie Delfini,Alexandre Eusebio,Frédérique Fluchère,Laura Mundler,Mathieu Anheim,Celine Julié,Ouhaid Lagha Boukbiza,Nadine Longato,Gabrielle Rudolf,Christine Tranchant,Marie-Agathe Zimmermann,Christoph Michael Kosinski,Eva Milkereit,Daniela Probst,Kathrin Reetz,Christian Sass,Johannes Schiefer,Christiane Schlangen,Cornelius J. Werner,Harald Gelderblom,Josef Priller,Harald Prüß,Eike Jakob Spruth,Gisa Ellrichmann,Lennard Herrmann,Rainer Hoffmann,Barbara Kaminski,Peter Kotz,Christian Prehn,Carsten Saft,Herwig W. Lange,Robert Maiwald,Matthias Löhle,Antonia Maass,Simone Schmidt,Cecile Bosredon,Alexander Storch,Annett Wolz,Martin Wolz,Philipp Capetian,Johann Lambeck,Birgit Zucker,Kai Boelmans,Christos Ganos,Walburgis Heinicke,Ute Hidding,Jan Lewerenz,Alexander Münchau,Jenny Schmalfeld,Lars Stubbe,Simone Zittel,Gabriele Diercks,Dirk Dressler,Heike Gorzolla,Christoph Schrader,Pawel Tacik,Michael Ribbat,Bernhard Longinus,Katrin Bürk,Jens Carsten Möller,Ida Rissling,Mark Mühlau,Alexander Peinemann,Michael Städtler,Adolf Weindl,Juliane Winkelmann,Cornelia Ziegler,N Bechtel,Heike Beckmann,S. Bohlen,E Hölzner,Ralf Reilmann,Stefanie Rohm,Silke Rumpf,Sigrun Schepers,Natalia Weber,Matthias Dose,Gabriele Leythäuser,Ralf Marquard,Tina Raab,Alexandra Wiedemann,Andrea Buck,Julia Connemann,Carolin Geitner,Andrea Kesse,Bernhard Landwehrmeyer,Christina Lang,Franziska Lezius,Solveig Nepper,Anke Niess,Ariane Schneider,Daniela Schwenk,Sigurd D. Süßmuth,Sonja Trautmann,Patrick Weydt,Claudia Cormio,Vittorio Sciruicchio,Claudia Serpino,Marina de Tommaso,Sabina Capellari,Pietro Cortelli,Roberto Galassi,Giovanni Rizzo,Roberto Poda,Cesa Scaglione,E Bertini,Elena Ghelli,Andrea Ginestroni,Francesca Massaro,Claudia Mechi,Marco Paganini,Silvia Piacentini,Silvia Pradella,Anna Maria Romoli,Sandro Sorbi,Giovanni Abbruzzese,Monica Bandettini di Poggio,Giovanna Ferrandes,Paola Mandich,Roberta Marchese,Alberto Albanese,Daniela Di Bella,Anna Castaldo,Stefano Di Donato,Cinzia Gellera,S. Genitrini,Caterina Mariotti,Lorenzo Nanetti,D. Paridi,Paola Soliveri,Chiara Tomasello,Giuseppe De Michele,Luigi Di Maio,Marco Massarelli,Silvio Peluso,Alessandro Roca,Cinzia Valeria Russo,Elena Salvatore,Pierpaolo Sorrentino,Enrico Amico,Mariagrazia Favellato,Annamaria Griguoli,Irene Mazzante,Martina Petrollini,Ferdinando Squitieri,Barbara D'Alessio,Chiara Esposito,Rita Bentivoglio,Marina Frontali,Arianna Guidubaldi,Tamara Ialongo,Gioia Jacopini,Carla Piano,Silvia Romano,Francesco Soleti,Maria Spadaro,Monique S.E. van Hout,Marloes E. Verhoeven,Jeroen P. P. van Vugt,A. Marit de Weert,J.J.W. Bolwijn,Marieke C. J. Dekker,B. Kremer,Klaus L. Leenders,J.C.H. van Oostrom,Simon J.A. van den Bogaard,Eve M. Dumas,Ellen P. Hart,Berry Kremer,C.C.P. Verstappen,Olaf Aaserud,Jan Frich C,Ragnhild Wehus,Kathrine Bjørgo,Madeleine Fannemel,Per F. Gørvell,Eirin Lorentzen,Lars Retterstøl,Bodil Stokke,Inga Bjørnevoll,Sigrid Botne Sando,Artur Dziadkiewicz,Malgorzata Nowak,Piotr Robowski,Emilia J. Sitek,Jarosław Sławek,Witold Sołtan,Michal Szinwelski,Magdalena Blaszcyk,Magdalena Boczarska-Jedynak,Ewelina Ciach-Wysocka,Agnieszka Gorzkowska,Barbara Jasinska-Myga,Gabriela Klodowska-Duda,Gregorz Opala,Daniel Stompel,Krzysztof Banaszkiewicz,Dorota Bocwinska,Kamila Bojakowska-Jaremek,Malgorzata Dec,Malgorzata Krawczyk,Monika Rudzińska,Elzbieta Szczygiel,Andrzej Szczudlik,Anna Wasielewska,Magdalena Wójcik,Anna Bryl,Anna Ciesielska,Aneta Klimberg,Jerzy T. Marcinkowski,Husam Samara,Justyna Sempolowicz,Anna Gogol,Piotr Janik,Hubert Kwieciński,Zygmunt Jamrozik,Jakub Antczak,Katarzyna Jachinska,Wioletta Krysa,Maryla Rakowicz,Przemyslaw Richter,Rafał Rola,Danuta Ryglewicz,Halina Sienkiewicz-Jarosz,Iwona Stepniak,Anna Sulek,Elzbieta Zdzienicka,Karolina Zieora-Jakutowicz,Joaquim J. Ferreira,Miguel Coelho,Tiago Mendes,Anabela Valadas,Carlos Andrade,Miguel Gago,Carolina Garrett,Maria Rosália Guerra,Carmen Durán Herrera,Patrocinio Moreno Garcia,Miquel Aguilar Barbera,Dolors Badenes Guia,Laura Casas Hernanz,Judit López Catena,Pilar Quiléz Ferrer,Ana Rojo Sebastián,Gemma Tome Carruesco,Jordi Bas,Núria Busquets,Matilde Calopa,Misericordia Floriach Robert,Celia Mareca Viladrich,Jesús Miguel Ruiz Idiago,Antonio Villa Riballo,Esther Cubo,Cecilia Gil Polo,Natividad Mariscal,Perez Jessica Rivadeneyra,Francisco J. Barrero,Blas Morales,María Fenollar,Rocío García-Ramos García,Paloma Ortega,Clara Villanueva,Javier Alegre,Mónica Bascuñana,Juan Garcia Caldentey,Marta Fatás Ventura,Guillermo García Ribas,Justo García de Yébenes,José Luis López-Sendón Moreno,Fernando Alonso Frech,Pedro J. Garcia Ruiz,Asunción Martinez-Descals,Rosa Guerrero,María José Saiz Artiga,Vicenta Sánchez,María Fuensanta Noguera Perea,Lorenza Fortuna,Salvadora Manzanares,Gema Reinante,María Martirio Antequera Torres,Laura Vivancos Moreau,Sonia González González,Luis Menéndez Guisasola,Carlos Salvador,Esther Suaréz San Martín,Inés Legarda Ramirez,Aranzazú Gorospe,Mónica Rodriguez Lopera,Penelope Navas Arques,María José Torres Rodríguez,Barbara Vives Pastor,Itziar Gaston,Maria Dolores Martinez-Jaurrieta,Jose Manuel Garcia Moreno,Carolina Mendez Lucena,Fatima Damas,Hermoso Eva Pacheco Cortegana,José Rafael Chacón Peña,Luis Redondo,Fátima Carrillo,María Teresa Cáceres,Pablo Mir,María José Lama Suarez,Laura Vargas-González,Maria E. Bosca,Francisco Castera Brugada,Juan Andres Burguera,Anabel Campos,Garcia Carmen Peiró Vilaplana,Peter Berglund,Radu Constantinescu,Gunnel Fredlund,Ulrika Høsterey-Ugander,Petra Linnsand,Liselotte Neleborn-Lingefjärd,Magnus Wentzel,Ghada Loutfi,Carina Olofsson,Eva-Lena Stattin,Laila Westman,Birgitta Wikström,Yanik Stebler,Alain Kaelin,Irene Romero,Michael Schüpbach,Sabine Weber Zaugg,Maria Hauer,Roman Gonzenbach,Hans H. Jung,Violeta Mihaylova,Jens Petersen,Roisin Jack,Kirsty Matheson,Zosia Miedzybrodzka,Daniela Rae,Sheila A. Simpson,Fiona Summers,Alexandra Ure,Vivien Vaughan,Shahbana Akhtar,Jenny Crooks,Adrienne Curtis,Jenny de Souza,John Piedad,Hugh Rickards,Jan Wright,Elizabeth Coulthard,Louise Gethin,Beverley Hayward,Kasia Sieradzan,Matthew Armstrong,Roger A. Barker,Deidre O'Keefe,Anna Di Pietro,Kate Fisher,Anna O. G. Goodman,Susan Hill,Ann Kershaw,Sarah L Mason,Nicole S. Paterson,Lucy Raymond,Rachel Swain,Natalie Valle Guzman,Monica Busse,Cynthia Butcher,Catherine Clenaghan,Sarah E. Hunt,Lesley Jones,Una Jones,Hanan Khalil,Michael John Owen,Kathleen Price,Anne Elizabeth Rosser,Maureen Edwards,Carrie Ho,Teresa Hughes,Marie McGill,Pauline Pearson,Mary Porteous,Paul Smith,Peter Brockie,Jillian Foster,Nicola Johns,Sue McKenzie,Jean Rothery,Gareth Thomas,Shona Yates,Liz Burrows,Carol Chu,Amy Fletcher,Deena Gallantrae,Stephanie Hamer,Alison Harding,Stefan Klöppel,Alison Kraus,Fiona Laver,Monica Lewis,Mandy Longthorpe,Ivana Marková,Ashok Raman,Nicola J. Robertson,Mark Silva,Aileen Thomson,Sue Wild,Pam Yardumian,Carole Evans,Deena Gallentrae,Emma Hobson,Stuart Jamieson,Hannah Musgrave,Liz Rowett,Jean Toscano,Colin Bourne,Jackie Clapton,Carole Clayton,Heather Dipple,Dawn Freire-Patino,Janet Grant,Diana Gross,Caroline Hallam,Julia Middleton,Ann Murch,Catherine Thompson,Sundus Alusi,Rhys Davies,Kevin Foy,Emily Gerrans,Louise Pate,Thomasin C. Andrews,Andrew Dougherty,Charlotte Golding,Fred Kavalier,Hana Laing,Alison Lashwood,Dene Robertson,Deborah Ruddy,Alastair Santhouse,Anna Whaite,Stefania Bruno,Karen M. Doherty,Salman Haider,Davina Hensman,Nayana Lahiri,Marianne Novak,Aakta Patel,Elisabeth Rosser,Rachel Taylor,Thomas T. Warner,Edward J. Wild,Natalie Arran,Judith Bek,David Craufurd,Marianne Hare,Liz Howard,Susan Huson,Liz Johnson,Mary Jones,Helen Murphy,Emma Oughton,Lucy Partington-Jones,Dawn Rogers,Andrea C. Sollom,Julie S. Snowden,Cheryl L. Stopford,Jennifer C. Thompson,Iris Trender-Gerhard,Nichola Verstraelen,Leann Westmoreland,Richard J. E. Armstrong,Kathryn Dixon,Andrea H. Németh,Gill Siuda,Ruth Valentine,David J. Harrison,Max Hughes,Andrew Parkinson,Beverley Soltysiak,Oliver Bandmann,Alyson Bradbury,Paul Gill,Helen Fairtlough,Kay Fillingham,Isabella Foustanos,Mbombe Kazoka,Kirsty L O'Donovan,Cat Taylor,Katherine Tidswell,Oliver Quarrell,Puay Ngoh Lau,Emmanul Pica,Louis C. Tan,Peter Holmans,Sarah J. Tabrizi +734 more
TL;DR: A novel measure of disease progression and a genome-wide significant signal on chromosome 5 spanning three genes: MSH3, DHFR, and MTRNR2L2 is generated, suggesting this mechanism as an area for future therapeutic investigation.
Journal ArticleDOI
Parkin disease: a clinicopathologic entity?
Karen M. Doherty,Laura Silveira-Moriyama,Laura Silveira-Moriyama,Laura Parkkinen,Daniel G. Healy,Michael A. Farrell,Niccolo E. Mencacci,Zeshan Ahmed,Francesca Brett,John Hardy,Niall Quinn,Timothy J. Counihan,Timothy Lynch,Zoe Fox,Tamas Revesz,Andrew J. Lees,Janice L. Holton +16 more
TL;DR: These findings support the notion that parkin disease is characterized by a more restricted morphologic abnormality than is found in PD, with predominantly ventral nigral degeneration and absent or rare Lewy bodies.
Journal ArticleDOI
Bone health in Parkinson's disease: a systematic review and meta-analysis.
Kelli M. Torsney,Alastair J. Noyce,Karen M. Doherty,Jonathan P. Bestwick,Ruth Dobson,Andrew J. Lees +5 more
TL;DR: In this paper, a systematic review and meta-analysis was performed to evaluate the relationship of Parkinson9s disease with osteoporosis, bone mineral density (BMD), and fracture risk.
Journal ArticleDOI
Decision making, impulsivity, and addictions: Do Parkinson's disease patients jump to conclusions?
Atbin Djamshidian,Sean S. O'Sullivan,Y Sanotsky,Stephen Sharman,Yuriy Matviyenko,Thomas Foltynie,Rosanna Michalczuk,Iciar Aviles-Olmos,Ludmyla Fedoryshyn,Karen M. Doherty,Yuriy Filts,Marianna Selikhova,Henrietta Bowden-Jones,Eileen M. Joyce,Andrew J. Lees,Bruno B. Averbeck,Bruno B. Averbeck +16 more
TL;DR: PD patients who had an ICB showed similar behavior to illicit substance abusers, whereas patients without ICBs more closely resembled pathological gamblers, and there was no difference in working memory performance within the PD groups.