B
Bart Van Puyvelde
Researcher at Ghent University
Publications - 24
Citations - 159
Bart Van Puyvelde is an academic researcher from Ghent University. The author has contributed to research in topics: Biology & Medicine. The author has an hindex of 4, co-authored 16 publications receiving 53 citations.
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Journal ArticleDOI
Removing the Hidden Data Dependency of DIA with Predicted Spectral Libraries.
Bart Van Puyvelde,Sander Willems,Ralf Gabriels,Simon Daled,Laura De Clerck,Sofie Vande Casteele,An Staes,Francis Impens,Dieter Deforce,Lennart Martens,Sven Degroeve,Maarten Dhaenens +11 more
TL;DR: DIA can be redeemed from this dependency by combining predicted fragment intensities and retention times with narrow window DIA, eliminating variation in library building and omits stochastic sampling, finally making the DIA workflow fully deterministic.
Journal ArticleDOI
Cov-MS: A Community-Based Template Assay for Mass-Spectrometry-Based Protein Detection in SARS-CoV-2 Patients
Bart Van Puyvelde,Katleen Van Uytfanghe,Olivier Tytgat,Olivier Tytgat,Laurence Van Oudenhove,Ralf Gabriels,Robbin Bouwmeester,Simon Daled,Tim Van Den Bossche,Pathmanaban Ramasamy,Sigrid Verhelst,Laura De Clerck,Laura Corveleyn,Sander Willems,Nathan Debunne,Evelien Wynendaele,Bart De Spiegeleer,Péter Judák,K. Roels,Laurie De Wilde,Peter Van Eenoo,Tim Reyns,Marc Cherlet,Emmie Dumont,Griet Debyser,Ruben t’Kindt,Koen Sandra,Surya Gupta,Nicolas Drouin,Amy C. Harms,Thomas Hankemeier,Donald J. L. Jones,Pankaj Gupta,Dan Lane,Catherine S. Lane,Said El Ouadi,Jean-Baptiste Vincendet,Nick Morrice,Stuart A. Oehrle,Nikunj Tanna,Steve Silvester,Sally Hannam,Florian C. Sigloch,Andrea Bhangu-Uhlmann,Jan Claereboudt,N. Leigh Anderson,Morteza Razavi,Sven Degroeve,Lize Cuypers,Christophe P. Stove,Katrien Lagrou,Geert A. Martens,Dieter Deforce,Lennart Martens,Johannes P. C. Vissers,Maarten Dhaenens +55 more
TL;DR: This paper has developed an alternative diagnostic test that detects proteolytically digested SARS-CoV-2 proteins using mass spectrometry (MS), and provides an orthogonal and complementary approach to RT-PCR using other reagents that are relatively inexpensive and widely available, as well as orthogonally skilled personnel and different instruments.
Journal ArticleDOI
Front Cover: Removing the Hidden Data Dependency of DIA with Predicted Spectral Libraries
Bart Van Puyvelde,Sander Willems,Ralf Gabriels,Simon Daled,Laura De Clerck,Sofie Vande Casteele,An Staes,Francis Impens,Dieter Deforce,Lennart Martens,Sven Degroeve,Maarten Dhaenens +11 more
Journal ArticleDOI
hSWATH: Unlocking SWATH's Full Potential for an Untargeted Histone Perspective.
Laura De Clerck,Sander Willems,Roberta Noberini,Camilla Restellini,Bart Van Puyvelde,Simon Daled,Tiziana Bonaldi,Dieter Deforce,Maarten Dhaenens +8 more
TL;DR: A complete SWATH workflow specifically adapted for the untargeted study of histones (hSWATH) is presented and its validity is assessed on a technical dataset of a time-lapse deacetylation of a commercial histone extract using HDAC1, which contains a ground truth.
Journal ArticleDOI
Ferroptosis Induction in Multiple Myeloma Cells Triggers DNA Methylation and Histone Modification Changes Associated with Cellular Senescence
Emilie Logie,Bart Van Puyvelde,Bart Cuypers,Anne Schepers,Herald Berghmans,Jelle Verdonck,Kris Laukens,Lode Godderis,Maarten Dhaenens,Dieter Deforce,Wim Vanden Berghe +10 more
TL;DR: In this paper, the authors found that MM1 multiple myeloma cells are sensitive to ferroptosis induction and epigenetic reprogramming by RSL3, irrespective of their glucocorticoid-sensitivity status.