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Showing papers by "Bas Teusink published in 1995"

Journal Article•DOI•
Energy, control and DNA structure in the living cell.

[...]

J.E. Wijker1, Peter Ruhdal Jensen2, Jacky L. Snoep1, A. Vaz Gomes1, Myriam Guiral1, A. P. M. Jongsma1, A. de Waal1, Sjouke Hoving1, S. van Dooren1, C.C. van der Weijden1, M. van Workum1, W.C. van Heeswijk1, O. Molenaar1, Peter R. Wielinga1, Peter Richard3, Jasper A. Diderich3, Barbara M. Bakker3, Bas Teusink3, Mirte B. Hemker3, Johann M. Rohwer3, A.A. van der Gugten1, Boris N. Kholodenko4, Hans V. Westerhoff3 •
Netherlands Cancer Institute1, Technical University of Denmark2, University of Amsterdam3, Moscow State University4
01 Jun 1995-Biophysical Chemistry
TL;DR: The extent to which the intracellular ATP level is involved in the control of cell physiology, how the elaborate control ofcell function may be analyzed theoretically and quantitatively, and if this can be utilized selectively to affect certain cell types are addressed.

19 citations

Journal Article•DOI•
Hierarchies in control

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Peter Ruhdal Jensen1, A.A. van der Gugten2, Martin Bier3, W.C. van Heeswijk2, W.C. van Heeswijk4, Johann M. Rohwer2, Douwe Molenaar2, M. van Workum2, Peter Richard, Bas Teusink4, Barbara M. Bakker4, Boris N. Kholodenko4, Boris N. Kholodenko5, Hans V. Westerhoff4, Hans V. Westerhoff2 •
Technical University of Denmark1, Netherlands Cancer Institute2, University of Chicago3, University of Amsterdam4, Moscow State University5
01 Mar 1995-Journal of Biological Systems
TL;DR: In this paper, the authors discuss that cell function is organized in hierarchical substructures and briefly touch on the topics of metabolic control and regulated gene expression, time dependent metabolism in intact yeast cells, and metabolite channelling.
Abstract: The living cell functions by virtue of an enormous number of different processes. It is one of the most difficult challenges of modern biology to elucidate how all those processes are coordinated quantitatively so as to lead to a viable system with optimal responses to various changes in the environment. The biochemical and biophysical processes of the living cell do not constitute a network with random connections. In this paper we shall discuss that cell function is organized in hierarchical substructures. We will briefly touch on the topics of (i) metabolic control and regulated gene expression, (ii) time dependent metabolism in intact yeast cells, and (iii) metabolite channelling.

4 citations