J
Johann M. Rohwer
Researcher at Stellenbosch University
Publications - 85
Citations - 3157
Johann M. Rohwer is an academic researcher from Stellenbosch University. The author has contributed to research in topics: Flux (metabolism) & Python (programming language). The author has an hindex of 29, co-authored 80 publications receiving 2822 citations. Previous affiliations of Johann M. Rohwer include Humboldt University of Berlin & Max Planck Society.
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Journal ArticleDOI
Ribosome and transcript copy numbers, polysome occupancy and enzyme dynamics in Arabidopsis
Maria Piques,Waltraud X. Schulze,Melanie Höhne,Björn Usadel,Yves Gibon,Johann M. Rohwer,Mark Stitt +6 more
TL;DR: Quantitative molecular information about the numbers of ribosomes, of transcripts for 35 enzymes in central metabolism and their loading into polysomes is used to estimate translation rates in Arabidopsis rosettes, and the consequences for important sub‐processes in plant growth are explored.
Journal ArticleDOI
Analysis of sucrose accumulation in the sugar cane culm on the basis of in vitro kinetic data
TL;DR: In view of the modelling results, overexpression of the fructose or glucose transporter or the vacuolar sucrose import protein, as well as reduction of cytosolic neutral invertase levels, appear to be the most promising targets for genetic manipulation.
Journal ArticleDOI
Modelling cellular systems with PySCeS
TL;DR: The Python Simulator for Cellular Systems (PySCeS) is an extendable research tool for the numerical analysis and investigation of cellular systems.
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SBML Level 3: an extensible format for the exchange and reuse of biological models
Sarah M. Keating,Sarah M. Keating,Dagmar Waltemath,Matthias König,Fengkai Zhang,Andreas Dräger,Claudine Chaouiya,Claudine Chaouiya,Frank Bergmann,Andrew Finney,Colin S. Gillespie,Tomáš Helikar,Stefan Hoops,Rahuman S Malik-Sheriff,Stuart L. Moodie,Ion I. Moraru,Chris J. Myers,Aurélien Naldi,Brett G. Olivier,Brett G. Olivier,Brett G. Olivier,Sven Sahle,James C. Schaff,Lucian P. Smith,Lucian P. Smith,Maciej J. Swat,Denis Thieffry,Leandro Watanabe,Darren J. Wilkinson,Darren J. Wilkinson,Michael L. Blinov,Kimberly Begley,James R. Faeder,Harold F. Gómez,Thomas M. Hamm,Yuichiro Inagaki,Wolfram Liebermeister,Allyson L. Lister,Daniel Lucio,Eric Mjolsness,Carole J. Proctor,Karthik Raman,Nicolas Rodriguez,Clifford A. Shaffer,Bruce E. Shapiro,Joerg Stelling,Neil Swainston,Naoki Tanimura,John Wagner,Martin Meier-Schellersheim,Herbert M. Sauro,Bernhard O. Palsson,Hamid Bolouri,Hiroaki Kitano,Akira Funahashi,Henning Hermjakob,John Doyle,Michael Hucka,Richard R. Adams,Nicholas Alexander Allen,Bastian R. Angermann,Marco Antoniotti,Gary D. Bader,Jan Červený,Mélanie Courtot,Christopher Cox,Piero Dalle Pezze,Emek Demir,William S. Denney,Harish Dharuri,Julien Dorier,Dirk Drasdo,Ali Ebrahim,Johannes Eichner,Johan Elf,Lukas Endler,Chris T. Evelo,Christoph Flamm,Ronan M. T. Fleming,Martina Fröhlich,Mihai Glont,Emanuel Gonçalves,Martin Golebiewski,Hovakim Grabski,Alex Gutteridge,Damon Hachmeister,Leonard A. Harris,Benjamin D. Heavner,Ron Henkel,William S. Hlavacek,Bin Hu,Daniel R. Hyduke,Hidde de Jong,Nick Juty,Peter D. Karp,Jonathan R. Karr,Douglas B. Kell,Roland Keller,Ilya Kiselev,Steffen Klamt,Edda Klipp,Christian Knüpfer,Fedor A. Kolpakov,Falko Krause,Martina Kutmon,Camille Laibe,Conor Lawless,Lu Li,Leslie M. Loew,Rainer Machné,Yukiko Matsuoka,Pedro Mendes,Huaiyu Mi,Florian Mittag,Pedro T. Monteiro,Kedar Nath Natarajan,Poul M. F. Nielsen,Tramy Nguyen,Alida Palmisano,Jean-Baptiste Pettit,Thomas Pfau,Robert Phair,Tomas Radivoyevitch,Johann M. Rohwer,Oliver A. Ruebenacker,Julio Saez-Rodriguez,Martin Scharm,Henning Schmidt,Falk Schreiber,Michael Schubert,Roman Schulte,Stuart C. Sealfon,Kieran Smallbone,Sylvain Soliman,Melanie I. Stefan,Devin P. Sullivan,Koichi Takahashi,Bas Teusink,David Tolnay,Ibrahim Vazirabad,Axel von Kamp,Ulrike Wittig,Clemens Wrzodek,Finja Wrzodek,Ioannis Xenarios,Anna Zhukova,Jeremy Zucker +146 more
TL;DR: The latest edition of the Systems Biology Markup Language (SBML) is reviewed, a format designed for this purpose that leverages two decades of SBML and a rich software ecosystem that transformed how systems biologists build and interact with models.
Journal ArticleDOI
Network Analysis of Enzyme Activities and Metabolite Levels and Their Relationship to Biomass in a Large Panel of Arabidopsis Accessions
Ronan Sulpice,Sandra Trenkamp,Matthias Steinfath,Björn Usadel,Yves Gibon,Hanna Witucka-Wall,Eva-Theresa Pyl,Hendrik Tschoep,Marie Caroline Steinhauser,Manuela Guenther,Melanie Hoehne,Johann M. Rohwer,Johann M. Rohwer,Thomas Altmann,Alisdair R. Fernie,Mark Stitt +15 more
TL;DR: This work profile maximum catalytic activities of 37 enzymes from central metabolism and generate a matrix to investigate species-wide connectivity between metabolites, enzymes, and biomass and shows that biomass can be predicted by two independent integrative metabolic biomarkers: preferential investment in photosynthetic machinery and optimization of carbon use.