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Beela Sarah Mathew

Researcher at Queen's University

Publications -  28
Citations -  3077

Beela Sarah Mathew is an academic researcher from Queen's University. The author has contributed to research in topics: Breast cancer & Cancer. The author has an hindex of 16, co-authored 26 publications receiving 2767 citations.

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Long-term effects of continuing adjuvant tamoxifen to 10 years versus stopping at 5 years after diagnosis of oestrogen receptor-positive breast cancer: ATLAS, a randomised trial

TL;DR: Treatment allocation seemed to have no effect on breast cancer outcome among 1248 women with ER-negative disease, and an intermediate effect among 4800 women with unknown ER status, and a further reduction in recurrence and mortality, particularly after year 10.
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Remission of oral leukoplakias and micronuclei in tobacco/betel quid chewers treated with beta-carotene and with beta-carotene plus vitamin A.

TL;DR: In this article, a short-term intervention trial of fishermen who chewed tobacco-containing betel quids daily (17.2 +/- 9.6 quids per day) and developed oral leukoplakias with elevated frequencies of micronucleated cells was conducted.
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Response of oral leukoplakias to the administration of vitamin A

TL;DR: Tobacco/betel nut chewers with well-developed oral leukoplakias were chosen for a short-term intervention trial of vitamin A therapy and the results were substantiated by examining the histological and cytological changes on small biopsies which were taken at the onset and at the completion of the trial period.
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Polymorphisms in DNA repair gene XRCC1 and increased genetic susceptibility to breast cancer.

TL;DR: Preliminary results based on the analysis of functionally relevant polymorphisms in XRCC1 low penetrance gene may provide a better model that would exhibit additive effects on individual susceptibility to breast cancer.
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Socioeconomic status, lifestyle factors and oral premalignant lesions

TL;DR: Higher SES index, education and income were associated with decreased risk of oral premalignant lesions in the authors' study, and the mechanism for the association is not clear.