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Beena Neelam
Researcher at Science Applications International Corporation
Publications - 5
Citations - 593
Beena Neelam is an academic researcher from Science Applications International Corporation. The author has contributed to research in topics: Gene & Genome. The author has an hindex of 5, co-authored 5 publications receiving 542 citations.
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Journal ArticleDOI
Initial sequence and comparative analysis of the cat genome
Joan Pontius,James C. Mullikin,Douglas Smith,Agencourt Sequencing Team,Kerstin Lindblad-Toh,Sante Gnerre,Michele Clamp,Jean Chang,Robert M. Stephens,Beena Neelam,Natalia Volfovsky,Alejandro A. Schäffer,Richa Agarwala,Kristina Narfström,William J. Murphy,Urs Giger,Alfred L. Roca,Agostinho Antunes,Agostinho Antunes,Marilyn Menotti-Raymond,Naoya Yuhki,Jill Pecon-Slattery,Warren E. Johnson,Guillaume Bourque,Glenn Tesler,Nisc Comparative Sequencing Program,Stephen J. O'Brien +26 more
TL;DR: The genome sequence of an inbred Abyssinian domestic cat was assembled, mapped, and annotated with a comparative approach that involved cross-reference to annotated genome assemblies of six mammals, shedding new light on the tempo and mode of gene/genome evolution in mammals and promising several research applications for the cat.
Journal ArticleDOI
A homozygous single-base deletion in MLPH causes the dilute coat color phenotype in the domestic cat.
Yasuko Ishida,Victor A. David,Eduardo Eizirik,Alejandro A. Schäffer,Beena Neelam,Melody E. Roelke,Steven S. Hannah,Stephen J. O'Brien,Marilyn Menotti-Raymond +8 more
TL;DR: In this article, the authors performed linkage mapping with microsatellites in a large multigeneration pedigree of domestic cats and detected tight linkage for dilute on cat chromosome C1 (θ=0.08, LOD=10.81).
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A 1.5-Mb-resolution radiation hybrid map of the cat genome and comparative analysis with the canine and human genomes.
William J. Murphy,Brian W. Davis,Victor A. David,Richa Agarwala,Alejandro A. Schäffer,Alison J. Pearks Wilkerson,Beena Neelam,Stephen J. O'Brien,Marilyn Menotti-Raymond +8 more
TL;DR: The improved RH comparative map provides a useful tool to facilitate positional cloning studies in the feline model and refined the pseudoautosomal region and boundary in the cat and show that it is markedly longer than those of human or mouse.
Journal ArticleDOI
Comparative Genomic Structure of Human, Dog, and Cat MHC: HLA, DLA, and FLA
TL;DR: Comparisons of the genomic structure of 3 mammalian major histocompatibility complexes (MHCs), human HLA, canine DLA, and feline FLA revealed remarkable structural differences between HLA and the other 2 MHCs, suggesting the dynamic nature in the evolution of MHC class I genes.
Journal ArticleDOI
Development of simple sequence repeat markers for the soybean rust fungus, Phakopsora pachyrhizi.
Sharon J. Anderson,Christine L. Stone,Martha Lucia Posada-Buitrago,Jeffrey L. Boore,Beena Neelam,Robert M. Stephens,Douglas G. Luster,Reid D. Frederick,Kerry F. Pedley +8 more
TL;DR: Twenty‐four simple sequence repeat markers were developed for Phakopsora pachyrhizi, a fungal pathogen of soybean (Glycine max) and other legumes, and a preliminary screen with the closely related species, P. meibomiae, indicated that these primer pairs are specific to P. pachyrsizi.