A
Alfred L. Roca
Researcher at University of Illinois at Urbana–Champaign
Publications - 107
Citations - 4514
Alfred L. Roca is an academic researcher from University of Illinois at Urbana–Champaign. The author has contributed to research in topics: Population & Koala retrovirus. The author has an hindex of 34, co-authored 98 publications receiving 4011 citations. Previous affiliations of Alfred L. Roca include National Institutes of Health & Urbana University.
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Journal ArticleDOI
The Near Eastern Origin of Cat Domestication
Carlos A. Driscoll,Marilyn Menotti-Raymond,Alfred L. Roca,Karsten Hupe,Warren E. Johnson,Eli Geffen,Eric H. Harley,Miguel Delibes,Dominique Pontier,Andrew C. Kitchener,Nobuyuki Yamaguchi,Stephen J. O'Brien,David W. Macdonald +12 more
TL;DR: A genetic assessment of 979 domestic cats and their wild progenitors revealed that cats were domesticated in the Near East, probably coincident with agricultural village development in the Fertile Crescent.
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SmileFinder: A Resampling-Based Approach to Evaluate Signatures of Selection from Genome-Wide Sets of Matching Allele Frequency Data in Two or More Diploid Populations
Wilfried Guiblet,Kai Zhao,Stephen J. O'Brien,Stephen J. O'Brien,Steven E. Massey,Alfred L. Roca,Taras K. Oleksyk +6 more
TL;DR: The output from SmileFinder can be used to plot percentile values to look for population diversity and divergence patterns that may suggest past actions of positive selection along chromosome maps, and to compare lists of suspected candidate genes under random gene sets to test for the overrepresentation of these patterns among gene categories.
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Initial sequence and comparative analysis of the cat genome
Joan Pontius,James C. Mullikin,Douglas Smith,Agencourt Sequencing Team,Kerstin Lindblad-Toh,Sante Gnerre,Michele Clamp,Jean Chang,Robert M. Stephens,Beena Neelam,Natalia Volfovsky,Alejandro A. Schäffer,Richa Agarwala,Kristina Narfström,William J. Murphy,Urs Giger,Alfred L. Roca,Agostinho Antunes,Agostinho Antunes,Marilyn Menotti-Raymond,Naoya Yuhki,Jill Pecon-Slattery,Warren E. Johnson,Guillaume Bourque,Glenn Tesler,Nisc Comparative Sequencing Program,Stephen J. O'Brien +26 more
TL;DR: The genome sequence of an inbred Abyssinian domestic cat was assembled, mapped, and annotated with a comparative approach that involved cross-reference to annotated genome assemblies of six mammals, shedding new light on the tempo and mode of gene/genome evolution in mammals and promising several research applications for the cat.
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Genetic Evidence for Two Species of Elephant in Africa
TL;DR: Dart-biopsy samples from 195 free-ranging African elephants in 21 populations were examined for DNA sequence variation in four nuclear genes and showed large genetic distance, multiple genetically fixed nucleotide site differences, morphological and habitat distinctions, and extremely limited hybridization of gene flow support the recognition and conservation management of two African species.
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Cytonuclear Genomic Dissociation in African Elephant Species
TL;DR: The persistence of residual forest elephant mitochondria in savanna elephant herds renders evolutionary interpretations based on mitochondrial DNA alone misleading and preserves a genomic record of ancient habitat changes.