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Brian W. Davis
Researcher at Texas A&M University
Publications - 66
Citations - 3221
Brian W. Davis is an academic researcher from Texas A&M University. The author has contributed to research in topics: Genome & Population. The author has an hindex of 27, co-authored 60 publications receiving 2362 citations. Previous affiliations of Brian W. Davis include Hospital Corporation of America & Texas A&M Health Science Center College of Medicine.
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Journal ArticleDOI
Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks.
Gina M. Peloso,Paul L. Auer,Joshua C. Bis,Arend Voorman,Alanna C. Morrison,Nathan O. Stitziel,Jennifer A. Brody,Sumeet A. Khetarpal,Jacy R Crosby,Myriam Fornage,Aaron Isaacs,Johanna Jakobsdottir,Mary F. Feitosa,Gail Davies,Jennifer E. Huffman,Ani Manichaikul,Brian W. Davis,Kurt Lohman,Aron Y. Joon,Albert V. Smith,Megan L. Grove,Paolo Zanoni,Valeska Redon,Serkalem Demissie,Kim Lawson,Ulrike Peters,Christopher S. Carlson,Rebecca D. Jackson,Kelli K. Ryckman,Rachel H. Mackey,Jennifer G. Robinson,David S. Siscovick,Pamela J. Schreiner,Josyf C. Mychaleckyj,James S. Pankow,Albert Hofman,André G. Uitterlinden,Tamara B. Harris,Kent D. Taylor,Jeanette M. Stafford,Lindsay M. Reynolds,Riccardo E. Marioni,Abbas Dehghan,Oscar H. Franco,Aniruddh P. Patel,Yingchang Lu,George Hindy,Omri Gottesman,Erwin P. Bottinger,Olle Melander,Marju Orho-Melander,Ruth J. F. Loos,Stefano Duga,Piera Angelica Merlini,Martin Farrall,Anuj Goel,Rosanna Asselta,Domenico Girelli,Nicola Martinelli,Svati H. Shah,William E. Kraus,Mingyao Li,Daniel J. Rader,Muredach P. Reilly,Ruth McPherson,Hugh Watkins,Diego Ardissino,Qunyuan Zhang,Judy Wang,Michael Y. Tsai,Herman A. Taylor,Adolfo Correa,Michael Griswold,Leslie A. Lange,John M. Starr,Igor Rudan,Gudny Eiriksdottir,Lenore J. Launer,Jose M. Ordovas,Daniel Levy,Y.-D. Ida Chen,Alexander P. Reiner,Caroline Hayward,Ozren Polasek,Ian J. Deary,Ingrid B. Borecki,Yongmei Liu,Vilmundur Gudnason,James G. Wilson,Cornelia M. van Duijn,Charles Kooperberg,Stephen S. Rich,Bruce M. Psaty,Jerome I. Rotter,Christopher J. O'Donnell,Kenneth Rice,Eric Boerwinkle,Sekar Kathiresan,L. Adrienne Cupples +98 more
TL;DR: Although the "Exome Array" was used to genotype >200,000 low-frequency and rare coding sequence variants across the genome in 56,538 individuals, none of these four variants was associated with risk for CHD, suggesting that examples of low- frequencies with robust effects on both lipids and CHD will be limited.
Journal ArticleDOI
Comparative analysis of the domestic cat genome reveals genetic signatures underlying feline biology and domestication
Michael J. Montague,Gang Li,Barbara Gandolfi,Razib Khan,Bronwen Aken,S. Searle,Patrick Minx,LaDeana W. Hillier,Daniel C. Koboldt,Brian W. Davis,Carlos A. Driscoll,Christina S. Barr,Kevin Blackistone,Javier Quilez,Belen Lorente-Galdos,Tomas Marques-Bonet,Can Alkan,Gregg W.C. Thomas,Matthew W. Hahn,Marilyn Menotti-Raymond,Stephen J. O'Brien,Stephen J. O'Brien,Richard K. Wilson,Leslie A. Lyons,William J. Murphy,Wesley C. Warren +25 more
TL;DR: Insight is provided into how the process of domestication altered the ancestral wildcat genome and build a resource for future disease mapping and phylogenomic studies across all members of the Felidae.
Journal ArticleDOI
Genomic Analyses Reveal the Influence of Geographic Origin, Migration, and Hybridization on Modern Dog Breed Development
Heidi G. Parker,Dayna L. Dreger,Maud Rimbault,Brian W. Davis,Alexandra B. Mullen,Gretchen Carpintero-Ramirez,Elaine A. Ostrander +6 more
TL;DR: These analyses characterize the complexities of breed development, resolving longstanding questions regarding individual breed origination, the effect of migration on geographically distinct breeds, and, by inference, transfer of trait and disease alleles among dog breeds.
Journal ArticleDOI
Phylogenomic evidence for ancient hybridization in the genomes of living cats (Felidae)
TL;DR: The first robust felid time tree that accounts for unique maternal, paternal, and biparental evolutionary histories is presented, highlighting the mosaic origin of modern felid genomes and the influence of sex chromosomes and sex-biased dispersal in post-speciation gene flow.
Journal ArticleDOI
Whole genome sequencing of canids reveals genomic regions under selection and variants influencing morphology
Jocelyn Plassais,Jaemin Kim,Brian W. Davis,Brian W. Davis,Danielle M. Karyadi,Andrew N. Hogan,Alex C. Harris,Brennan Decker,Brennan Decker,Heidi G. Parker,Elaine A. Ostrander +10 more
TL;DR: The results identify variants of strong impact associated with 16 phenotypes, including body weight variation which, when combined with existing data, explain greater than 90% of body size variation in dogs.