scispace - formally typeset
B

Benoit de Crombrugghe

Researcher at University of Texas MD Anderson Cancer Center

Publications -  148
Citations -  25751

Benoit de Crombrugghe is an academic researcher from University of Texas MD Anderson Cancer Center. The author has contributed to research in topics: Chondrocyte & Cellular differentiation. The author has an hindex of 75, co-authored 148 publications receiving 24008 citations. Previous affiliations of Benoit de Crombrugghe include National Institutes of Health & University of Texas at Austin.

Papers
More filters
Journal ArticleDOI

The Novel Zinc Finger-Containing Transcription Factor Osterix Is Required for Osteoblast Differentiation and Bone Formation

Kazuhisa Nakashima, +6 more
- 11 Jan 2002 - 
TL;DR: It is proposed that Runx2/Cbfa1-expressing preosteoblasts are still bipotential cells, because Osx null preostEoblasts express typical chondrocyte marker genes, and Osx acts downstream of Runx 2/C bfa1.
Journal ArticleDOI

Sox9 is required for cartilage formation.

Weimin Bi, +4 more
- 01 May 1999 - 
TL;DR: The results identify Sox9 as the first transcription factor that is essential for chondrocyte differentiation and cartilage formation and Sox9 is identified as a regulator of the chondROcyte lineage.
Journal ArticleDOI

The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6

Haruhiko Akiyama, +4 more
- 01 Nov 2002 - 
TL;DR: It is concluded that Sox9 is required during sequential steps of the chondrocyte differentiation pathway and is also needed to prevent conversion of proliferating chONDrocytes into hypertrophic chondROcytes.
Journal ArticleDOI

A new long form of Sox5 (L-Sox5), Sox6 and Sox9 are coexpressed in chondrogenesis and cooperatively activate the type II collagen gene

Véronique Lefebvre, +2 more
- 01 Oct 1998 - 
TL;DR: The data suggest that L‐Sox5/Sox6 and Sox9, which belong to two different classes of Sox transcription factors, cooperate with each other in expression of Col2a1 and possibly other genes of the chondrocytic program.
Journal ArticleDOI

Interactions between Sox9 and β-catenin control chondrocyte differentiation

Haruhiko Akiyama, +11 more
- 01 May 2004 - 
TL;DR: The results strongly suggest that chondrogenesis is controlled by interactions between Sox9 and the Wnt/β-catenin signaling pathway.