B
Bernard Bizzini
Researcher at Pierre-and-Marie-Curie University
Publications - 165
Citations - 3966
Bernard Bizzini is an academic researcher from Pierre-and-Marie-Curie University. The author has contributed to research in topics: Toxoid & Antigen. The author has an hindex of 31, co-authored 165 publications receiving 3898 citations. Previous affiliations of Bernard Bizzini include University of Zurich & Université libre de Bruxelles.
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Journal ArticleDOI
Adjuvants--a balance between toxicity and adjuvanticity.
Rajesh Gupta,Edgar H. Relyveld,Erik B. Lindblad,Bernard Bizzini,Shlomo Ben-Efraim,Chander Kanta Gupta +5 more
TL;DR: The most common adjuvants for human use today are still aluminium hydroxide, aluminium phosphate and calcium phosphate although oil emulsions, products from bacteria and their synthetic derivatives as well as liposomes have also been tested or used in humans.
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C-C Chemokines, Pivotal in Protection Against HIV Type 1 Infection
Daniel Zagury,Abderrahim Lachgar,Vida Chams,Lat S. Fall,Jacky Bernard,Jean-François Zagury,Bernard Bizzini,Alessandro Gringeri,Elena Santagostino,Jay Rappaport,Michael Feldman,Stephen J. O'Brien,Arsène Burny,Robert C. Gallo +13 more
TL;DR: In this paper, transient natural resistance over time of most of 128 hemophiliacs who were inoculated repeatedly with HIV-1-contaminated Factor VIII concentrate from plasma during 1980-1985 before the development of the HIV blood test.
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Tetanus toxin and botulinum A toxin inhibit release and uptake of various transmitters, as studied with particulate preparations from rat brain and spinal cord.
TL;DR: It is proposed that tetanus and botulinum A toxin act in a basically similar manner on a process underlying the function of synapses in general, and the pronounced sensitivity of glycine and GABA release from spinal cord, together with the axonal ascent of tetanus toxin, may be crucial in the pathogenesis of tetanos.
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Interferon α and Tat involvement in the immunosuppression of uninfected T cells and C-C chemokine decline in AIDS
Daniel Zagury,Abderrahim Lachgar,Vida Chams,Lat S. Fall,Jacky Bernard,Jean-François Zagury,Bernard Bizzini,Alessandro Gringeri,Elena Santagostino,Jay Rappaport,Michael Feldman,Arsène Burny,Robert C. Gallo +12 more
TL;DR: It is suggested that IFNalpha and Tat may be critical targets for anti-AIDS strategies because specific antibodies against these proteins prevent generation of suppressor cells in HIV-1-infected peripheral blood mononuclear cell cultures.
Journal Article
Antibodies to the HIV-1 Tat protein correlated with nonprogression to AIDS: a rationale for the use of Tat toxoid as an HIV-1 vaccine.
Jean-François Zagury,Anne M. Sill,William A. Blattner,Abderrahim Lachgar,H. Le Buanec,M Richardson,Jay Rappaport,Houria Hendel,Bernard Bizzini,Alessandro Gringeri,Miguel Carcagno,M Criscuolo,Arsène Burny,Robert C. Gallo,Daniel Zagury +14 more
TL;DR: Antibodies toward HIV-1 Tat, which are inversely correlated to p24 antigenemia, appear as a critical marker for a lack of disease progression, strongly suggests that rising anti-Tat antibodies through active immunization may be beneficial in AIDS vaccine development to control viral replication.