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Bernardo Léo Wajchenberg
Researcher at University of São Paulo
Publications - 170
Citations - 2323
Bernardo Léo Wajchenberg is an academic researcher from University of São Paulo. The author has contributed to research in topics: Insulin & Diabetes mellitus. The author has an hindex of 25, co-authored 170 publications receiving 2241 citations. Previous affiliations of Bernardo Léo Wajchenberg include University of Rio Grande.
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Determination of the source(s) of androgen overproduction in hirsutism associated with polycystic ovary syndrome by simultaneous adrenal and ovarian venous catheterization. Comparison with the dexamethasone suppression test.
Bernardo Léo Wajchenberg,Setsuko S. Achando,Helena Okada,Carlos Eduardo Czeresnia,Sérgio Peixoto,Sergio S. Lima,Jayme Goldman +6 more
TL;DR: In hirsutism associated with the PCOS, the predominant source of androgens is the ovaries and that glucocorticoid suppression cannot assign adrenal origin as the site of excessive androgens.
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Adipose tissue at the crossroads in the development of the metabolic syndrome, inflammation and atherosclerosis
TL;DR: The authors analyze insulin resistance, the metabolic syndrome and endothelial dysfunction as consequence of a common antecedent, a low grade inflammation, indicating that in obesity there is a chronically activated inflammatory state of the adipose tissue.
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Mutations in Gng3lg and AGPAT2 in Berardinelli-Seip Congenital Lipodystrophy and Brunzell Syndrome: Phenotype Variability Suggests Important Modifier Effects
Mao Fu,Rasa Kazlauskaite,Maria de Fátima Paiva Baracho,Maria Goretti do Nascimento Santos,José Brandão-Neto,Sandra M.F. Villares,Francesco S. Celi,Bernardo Léo Wajchenberg,Alan R. Shuldiner +8 more
TL;DR: Mutations in AGPAT2 and Gng3lg are approximately equally represented in CGL; despite harboring the same Gng 3lg mutation, subjects may have widely divergent clinical manifestations, suggesting modifying influences of other genes and/or environment; and Brunzell syndrome may be caused by a mutation in AG PAT2.
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Salivary cortisol for the evaluation of Cushing's syndrome
TL;DR: In patients suspected of having Cushing's syndrome dynamic tests can be performed in both plasma and saliva, however, in some samples, the salivary cortisol measurement appears advantageous over plasma cortisol determination.
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Moderate effect of duodenal-jejunal bypass surgery on glucose homeostasis in patients with type 2 diabetes.
Samuel Klein,Elisa Fabbrini,Bruce W. Patterson,Kenneth S. Polonsky,Carlos A. Schiavon,Jose L. Correa,João E. Salles,Bernardo Léo Wajchenberg,Ricardo Cohen +8 more
TL;DR: It is suggested that altering the intestinal site of delivery of ingested nutrients has moderate therapeutic effects by improving β‐cell function and glycemic control.