Bernd Köhler

TL;DR: CCM and skin biopsy both detect nerve fiber loss in recently diagnosed type 2 diabetes, but largely in different patients, suggesting a patchy manifestation pattern of small fiber neuropathy.

TL;DR: Both OCT and CLSM revealed signs of early neurodegenerative changes, e.g. thinning of distinct retinal layers at the pericentral ring and shortening of corneal nerve fibers that are already present in pediatric T1DM patients.

TL;DR: By providing an easy-to-use tool for obtaining large-scale mosaic images of the SNP, this technique has the potential to facilitate larger clinical trials where SNP morphology is used as a surrogate marker for peripheral neuropathy.

TL;DR: An in vivo confocal laser scanning microscopy based method for large 3D reconstruction of the cornea on a cellular level with cropped volume sizes up to 266 x 286 x 396 µm3 and a novel concave surface contact cap is presented.

TL;DR: World SBP patterns revealed marked degeneration of secondary nerve fiber branches outside the whorl region in long-duration diabetes and wide-area mosaic images provide reference values for mC NFL and wCNFL and reveal a progressive degenerations of the SBP with increasing duration of type 2 diabetes.