B
Bernd Schweizer
Researcher at ETH Zurich
Publications - 25
Citations - 1708
Bernd Schweizer is an academic researcher from ETH Zurich. The author has contributed to research in topics: Crystal structure & Crystal structure prediction. The author has an hindex of 14, co-authored 25 publications receiving 1639 citations.
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Journal ArticleDOI
Significant progress in predicting the crystal structures of small organic molecules--a report on the fourth blind test.
Graeme M. Day,Timothy G. Cooper,Aurora J. Cruz-Cabeza,Katarzyna E. Hejczyk,Herman L. Ammon,Stephan X. M. Boerrigter,Jeffrey S. Tan,Raffaele Guido Della Valle,Elisabetta Venuti,Jovan Jose,Shridhar R. Gadre,Gautam R. Desiraju,Tejender S. Thakur,Bouke P. van Eijck,Julio C. Facelli,Victor E. Bazterra,Marta B. Ferraro,D. W. M. Hofmann,Marcus A. Neumann,Frank J. J. Leusen,John Kendrick,Sarah L. Price,Alston J. Misquitta,Panagiotis G. Karamertzanis,Gareth W. A. Welch,Harold A. Scheraga,Yelena A. Arnautova,Martin U. Schmidt,Jacco van de Streek,Alexandra K. Wolf,Bernd Schweizer +30 more
TL;DR: The results reflect important improvements in modelling methods and suggest that, at least for the small and fairly rigid types of molecules included in this blind test, such calculations can be constructively applied to help understand crystallization and polymorphism of organic molecules.
Journal ArticleDOI
A third blind test of crystal structure prediction
Graeme M. Day,W. D. S. Motherwell,Herman L. Ammon,Stephan X. M. Boerrigter,R. G. Della Valle,Elisabetta Venuti,A. Dzyabchenko,Jack D. Dunitz,Bernd Schweizer,B.P. van Eijck,P. Erk,Julio C. Facelli,Victor E. Bazterra,Marta B. Ferraro,D. W. M. Hofmann,Frank J. J. Leusen,C. Liang,Constantinos C. Pantelides,Panagiotis G. Karamertzanis,Sarah L. Price,Thomas C. Lewis,Harriott Nowell,A. Torrisi,Harold A. Scheraga,Yelena A. Arnautova,Martin U. Schmidt,P. Verwer +26 more
TL;DR: A third blind test of crystal structure prediction was hosted by the Cambridge Crystallographic Data Centre and highlighted the necessity for better energy models, capable of simultaneously describing conformational and packing energies with high accuracy.
Journal ArticleDOI
Crystal structure prediction of small organic molecules: a second blind test
W.D.S. Motherwell,Herman L. Ammon,Jack D. Dunitz,A. Dzyabchenko,P. Erk,Angelo Gavezzotti,D. W. M. Hofmann,Frank J. J. Leusen,Jos P. M. Lommerse,W.T.M. Mooij,Sarah L. Price,Harold A. Scheraga,Bernd Schweizer,Martin U. Schmidt,B.P. van Eijck,P. Verwer,D.E. Williams +16 more
TL;DR: A measure of the success and failure of current methodologies is given, using the methodology wherein a molecular model is used to construct theoretical crystal structures in given space groups.
Journal ArticleDOI
Nucleic‐Acid Analogues with Constraint Conformational Flexibility in the Sugar‐Phosphate Backbone (‘Bicyclo‐DNA’). Part 1. Preparation of (3S,5′R)‐2′‐Deoxy‐3′,5′‐ethano‐αβ‐D‐ribonucleosides (‘Bicyclonucleosides’)
TL;DR: In this paper, the synthesis of 2′-deoxy-3′,5′-ethano-D-ribonucleosides 1−8 was described. But the synthesis was performed using an enantiomerically pure carbohydrate precursor 18/19 (Schemes 1, 2 and 3).
Journal ArticleDOI
Warum Pentose- und nicht Hexose-Nucleinsäuren??. Teil II. Oligonucleotide aus 2′,3′-Dideoxy-β-D-glucopyranosyl-Bausteinen (‘Homo-DNS’): Herstellung.†
Markus Böhringer,Hans-Jorg Roth,Jürg Hunziker,Michael W. Göbel,Ravichandran Krishnan,Alfred Giger,Bernd Schweizer,J. Schreiber,Christian J. Leumann,Albert Eschenmoser +9 more
TL;DR: In this article, the authors describe the preparation of 2.3D-dideoxy-β-D-glucopyranosyl-derived nucleosides of the five bases adenine, cytosine, guanine, thymine, and uracil as well as the synthesis of oligonucleotides derived from them.