B
Beverly L. Davidson
Researcher at Children's Hospital of Philadelphia
Publications - 410
Citations - 35019
Beverly L. Davidson is an academic researcher from Children's Hospital of Philadelphia. The author has contributed to research in topics: Gene silencing & RNA interference. The author has an hindex of 94, co-authored 391 publications receiving 33041 citations. Previous affiliations of Beverly L. Davidson include United States Department of Veterans Affairs & University of California, Los Angeles.
Papers
More filters
Posted ContentDOI
Design and validation of a multi-point injection technology for MR-guided convection enhanced delivery in the brain
Kayla Prezelski,Megan S. Keiser,Joel M. Stein,Timothy H. Lucas,Beverly L. Davidson,Pedro Gonzalez-Alegre,Flavia Vitale +6 more
TL;DR: In this article, a multi-point cannula specifically designed to optimize distribution and delivery time in MR-guided intracranial CED of gene-based therapeutics is presented.
Journal ArticleDOI
Author Correction: Regulated control of gene therapies by drug-induced splicing
SHORT COMMUNICATION Determination of the Mutations Responsible for the Lesch-Nyhan Syndrome in 17 Subjects'
Susan A. Tarl,Beverly L. Davidson,Veda C. Wu,Frank J. Zidar,J. Edwin Seegmiller,William N. Kelley,Thomas D. Palella +6 more
TL;DR: In this paper, direct sequencing of the polymerase chain reaction-amplified product of reverse-transcribed HPRT mRNA enabled the rapid identification of the mutations found in 17 previously uncharacterized cell lines derived from patients with the Lesch-Nyhan syndrome.
Patent
Crispr interference based htt allelic suppression and treatment of huntington disease
TL;DR: In this article, expression cassettes and vectors, such as viral (e.g., AAV) vectors, are provided, comprising a first nucleic acid encoding a nuclease defective Cas 9 (dCas9) polypeptide and a second nucleic acids encoding a guide polynucleotide that targets the dCas9 polyPEptide to the transcriptional start site of an allele encoding a mutant huntingtin gene (HTT)-encoded protein.