B
Bianba
Researcher at Kunming Institute of Zoology
Publications - 12
Citations - 560
Bianba is an academic researcher from Kunming Institute of Zoology. The author has contributed to research in topics: Population & Genome. The author has an hindex of 8, co-authored 12 publications receiving 420 citations. Previous affiliations of Bianba include Chinese Academy of Sciences.
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Journal ArticleDOI
Genetic Evidence of Paleolithic Colonization and Neolithic Expansion of Modern Humans on the Tibetan Plateau
Xuebin Qi,Chaoying Cui,Yi Peng,Yi Peng,Xiaoming Zhang,Xiaoming Zhang,Zhaohui Yang,Zhaohui Yang,Hua Zhong,Hui Zhang,Kun Xiang,Kun Xiang,Xiangyu Cao,Xiangyu Cao,Yi Wang,Yi Wang,Ouzhuluobu,Basang,Ciwangsangbu,Bianba,Gonggalanzi,Tianyi Wu,Hua Chen,Hong Shi,Bing Su +24 more
TL;DR: The genetic data indicate that Tibetans have been adapted to a high altitude environment since initial colonization of the Tibetan Plateau in the early Upper Paleolithic, before the last glacial maximum, followed by a rapid population expansion that coincided with the establishment of farming and yak pastoralism on the PlateauIn the early Neolithic.
Journal ArticleDOI
Identification of a Tibetan-specific mutation in the hypoxic gene EGLN1 and its contribution to high-altitude adaptation
Kun Xiang,Ouzhuluobu,Yi Peng,Zhaohui Yang,Zhaohui Yang,Xiaoming Zhang,Xiaoming Zhang,Chaoying Cui,Hui Zhang,Ming Li,Ming Li,Yanfeng Zhang,Bianba,Gonggalanzi,Basang,Ciwangsangbu,Tianyi Wu,Hua Chen,Hong Shi,Xuebin Qi,Bing Su +20 more
TL;DR: A significant association between rs186996510 and hemoglobin levels in Tibetans is detected, suggesting that EGLN1 contributes to the adaptively low hemoglobin level of Tibetans compared with acclimatized lowlanders at high altitude.
Journal ArticleDOI
Down-Regulation of EPAS1 Transcription and Genetic Adaptation of Tibetans to High-Altitude Hypoxia.
Yi Peng,Chaoying Cui,Yaoxi He,Yaoxi He,Ouzhuluobu,Hui Zhang,Deying Yang,Qu Zhang,Bianbazhuoma,Lixin Yang,Yibo He,Yibo He,Kun Xiang,Xiaoming Zhang,Sushil Bhandari,Peng Shi,Yangla,Dejiquzong,Baimakangzhuo,Duojizhuoma,Yongyue Pan,Cirenyangji,Baimayangji,Gonggalanzi,Caijuan Bai,Bianba,Basang,Ciwangsangbu,Shuhua Xu,Shuhua Xu,Hua Chen,Shiming Liu,Tianyi Wu,Xuebin Qi,Bing Su +34 more
TL;DR: It is proposed that the down-regulation of EPAS1 contributes to the molecular basis of Tibetans’ adaption to high-altitude hypoxia.
Journal ArticleDOI
HMOX2 Functions as a Modifier Gene for High-Altitude Adaptation in Tibetans.
Deying Yang,Deying Yang,Yi Peng,Ouzhuluobu,Bianbazhuoma,Chaoying Cui,Bianba,Liangbang Wang,Kun Xiang,Yaoxi He,Yaoxi He,Hui Zhang,Xiaoming Zhang,Jiewei Liu,Jiewei Liu,Hong Shi,Hong Shi,Yongyue Pan,Duojizhuoma,Dejiquzong,Cirenyangji,Baimakangzhuo,Gonggalanzi,Shimin Liu,Gengdeng,Tianyi Wu,Hua Chen,Xuebin Qi,Bing Su +28 more
TL;DR: It is proposed that HMOX2 contributes to high‐altitude adaptation in Tibetans by functioning as a modifier in the regulation of hemoglobin metabolism.
Journal ArticleDOI
Genetic evidence of a recent Tibetan ancestry to Sherpas in the Himalayan region
Sushil Bhandari,Xiaoming Zhang,Chaoying Cui,Bianba,Shiyu Liao,Yi Peng,Hui Zhang,Kun Xiang,Hong Shi,Hong Shi,Ouzhuluobu,Baimakongzhuo,Gonggalanzi,Shimin Liu,Gengdeng,Tianyi Wu,Xuebin Qi,Bing Su +17 more
TL;DR: DNA samples from 582 Sherpas living in Nepal and Tibet Autonomous Region of China showed that Sherpas share most of their paternal and maternal lineages with indigenous Tibetans, suggesting Tibetans are the ancestral populations of the Sherpas, whose adaptive traits for high altitude were recently inherited from their ancestors in Tibet.