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Biborka Bereczky
Researcher at Kyushu University
Publications - 8
Citations - 246
Biborka Bereczky is an academic researcher from Kyushu University. The author has contributed to research in topics: Endocytic cycle & Endocytosis. The author has an hindex of 6, co-authored 6 publications receiving 230 citations.
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Journal ArticleDOI
Role of macrophages in inflammatory lymphangiogenesis: Enhanced production of vascular endothelial growth factor C and D through NF-κB activation
Kosuke Watari,Shintaro Nakao,Abbas Fotovati,Yuji Basaki,Fumihito Hosoi,Biborka Bereczky,Ryuichi Higuchi,Tomofumi Miyamoto,Michihiko Kuwano,Mayumi Ono +9 more
TL;DR: It is found that proinflammatory cytokine, interleukin-1 beta (IL-1beta), could induce lymphangiogenesis in mouse cornea through enhanced production of potent lymphang iogenic factors, VEGF-A, V EGF-C and VEGf-D.
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The EGFR inhibitor gefitinib suppresses ligand-stimulated endocytosis of EGFR via the early/late endocytic pathway in non-small cell lung cancer cell lines.
TL;DR: Novel evidence is provided that efficient endocytosis of EGF–EGFR occurs via the endocytic pathway in the PC9 cells, because the internalized Texas red-EGF-positive small punctate vesicles were transported to the late endosomes/lysosomes and then degraded within the lysosomes after 60 min of internalization.
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Evidence for efficient phosphorylation of EGFR and rapid endocytosis of phosphorylated EGFR via the early/late endocytic pathway in a gefitinib-sensitive non-small cell lung cancer cell line
TL;DR: Novel evidence is provided that extensive impairment in pEGFR endocytosis via the early endocytic pathway might confer gefitinib-resistance in NSCLC cell lines, and an aberration in some steps of EGF-EGFR trafficking from the early endsomes to late endosomes/lysosomes occurs in QG56 cells.
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A role of LIM kinase 1/cofilin pathway in regulating endocytic trafficking of EGF receptor in human breast cancer cells
TL;DR: It is demonstrated that a marked delay in the receptor-mediated internalization of Texas red-labeled EGF was observed in the wild-type LIMK1 transfectants, and that most of the internalized EGF staining were accumulated within transferrin receptor-positive early endosomes even after 30 min internalization, implicate that LIMK 1 signaling indeed plays a pivotal role in the regulation of EGFR trafficking through the endocytic pathway in invasive tumor cells.