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Bing-Wen Soong

Researcher at Taipei Veterans General Hospital

Publications -  144
Citations -  5378

Bing-Wen Soong is an academic researcher from Taipei Veterans General Hospital. The author has contributed to research in topics: Spinocerebellar ataxia & Ataxia. The author has an hindex of 39, co-authored 141 publications receiving 4776 citations. Previous affiliations of Bing-Wen Soong include Taipei Medical University & National Institutes of Health.

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Expanding the phenotype of AFG3L2 mutations: Late-onset autosomal recessive spinocerebellar ataxia

TL;DR: In this paper, the clinical features and spectrum of AFG3L2 mutations in a Taiwanese cohort with cerebellar ataxia were delineated by targeted resequencing.
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Allele-specific All-or-None PCR Product Diagnostic Strategy for Charcot-Marie-Tooth 1A and Hereditary Neuropathy with Liability to Pressure Palsies

TL;DR: Stringently specific primers were used to overcome the problem of nonspecific amplification and provide a rapid, all‐or‐none PCR product and efficient screening test for CMT1A and HNPP.
Journal Article

Regional decrease in brain glucose metabolism in asymptomatic gene carriers of Machado-Joseph disease: a preliminary report.

TL;DR: The sensitivity of PET is sufficient to justify its routine use in the investigation of asymptomatic at-risk MJD subjects, and subclinical reduction of FDG consumption in the cerebellar hemisphere and occipital cortex is found to act as an objective marker of disease activity.
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Investigating TBP CAG/CAA trinucleotide repeat expansions in a Taiwanese cohort with ALS

TL;DR: In this paper, the role of similar trinucleotide repeat expansions in ATXN2 has been investigated for the development of amyotrophic lateral sclerosis (ALS) and showed that they are a genetic risk factor for the disease.
Journal Article

An electrophysiologic and pathologic study of peripheral nerves in individuals with Machado-Joseph disease.

TL;DR: Findings in MJD were similar to those seen in Friedreich's ataxia, suggesting a loss of sensory and motor fibers probably following a lesion of the dorsal root ganglion and the anterior horns in the spinal cord.