B
Bing-Wen Soong
Researcher at Taipei Veterans General Hospital
Publications - 144
Citations - 5378
Bing-Wen Soong is an academic researcher from Taipei Veterans General Hospital. The author has contributed to research in topics: Spinocerebellar ataxia & Ataxia. The author has an hindex of 39, co-authored 141 publications receiving 4776 citations. Previous affiliations of Bing-Wen Soong include Taipei Medical University & National Institutes of Health.
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Journal ArticleDOI
Comparison of cerebellar ataxias: A three-year prospective longitudinal assessment
Yi-Chung Lee,Yi-Chung Lee,Yi-Chu Liao,Po Shan Wang,I-Hui Lee,I-Hui Lee,Kon-Ping Lin,Kon-Ping Lin,Bing-Wen Soong,Bing-Wen Soong +9 more
TL;DR: It is shown that patients with multiple system atrophy‐cerebellar variant had a faster progression in gait, sitting, speech, and total score than patients with spinocerebelar ataxias.
Journal ArticleDOI
PRRT2 mutations in paroxysmal kinesigenic dyskinesia with infantile convulsions in a Taiwanese cohort.
Yi-Chung Lee,Ming-Jen Lee,Hsiang-Yu Yu,Hsiang-Yu Yu,Chien Chen,Chien Chen,Chang-Hung Hsu,Kon-Ping Lin,Kon-Ping Lin,Kwong-Kum Liao,Kwong-Kum Liao,Ming-Hong Chang,Yi-Chu Liao,Bing-Wen Soong,Bing-Wen Soong +14 more
TL;DR: This study expands the spectrum of PKD/IC-associated PR RT2 mutations, highlights the pathogenic role of PRRT2 mutations in PKD /IC, and suggests genetic heterogeneity within idiopathic PKD.
Journal ArticleDOI
Treatment of Spinocerebellar Ataxia With Mesenchymal Stem Cells: A Phase I/IIa Clinical Study.
Yun An Tsai,Ren Shyan Liu,Jiing Feng Lirng,Bang Hung Yang,Chin Hao Chang,Yi Chen Wang,Yu Shan Wu,Jennifer Hui Chun Ho,Oscar K. Lee,Oscar K. Lee,Bing-Wen Soong,Bing-Wen Soong +11 more
TL;DR: It is concluded that allogeneic MSCs given by intravenous injection seems to be safe and tolerable in patients with spinocerebellar ataxia type 3, thus supporting advancement of the clinical development of allogeneo-MSCs for the treatment of spinocephalic ataxias in a randomized, double-blind, placebo-controlled phase II trials.
Journal ArticleDOI
PRRT2 mutations lead to neuronal dysfunction and neurodevelopmental defects.
Yo-Tsen Liu,Fang-Shin Nian,Wan-Ju Chou,Chin-Yin Tai,Shang-Yeong Kwan,Shang-Yeong Kwan,Chien Chen,Chien Chen,Pei-Wen Kuo,Po-Hsi Lin,Chin-Yi Chen,Chia-Wei Huang,Yi-Chung Lee,Yi-Chung Lee,Bing-Wen Soong,Bing-Wen Soong,Jin Wu Tsai +16 more
TL;DR: It is found that knocking down Prrt2 expression in vivo resulted in a delay in neuronal migration during embryonic development and a marked decrease in synaptic density after birth, which may contribute to the severe clinical symptoms in PRRT2–related diseases.
Journal ArticleDOI
Exome sequencing identifies GNB4 mutations as a cause of dominant intermediate Charcot-Marie-Tooth disease.
Bing-Wen Soong,Yen Hua Huang,Pei-Chien Tsai,Chien Chang Huang,Hung Chuan Pan,Yi-Chun Lu,Hsin Ju Chien,Tze Tze Liu,Ming Hong Chang,Kon Ping Lin,Kon Ping Lin,Pang-Hsien Tu,Lung Sen Kao,Yi-Chung Lee,Yi-Chung Lee +14 more
TL;DR: GNB4 mutations are identified as a cause ofarcot-Marie-Tooth disease and the importance of Gβ4-related GPCR signaling in peripheral-nerve function in humans is highlighted.