B
Bing-Wen Soong
Researcher at Taipei Veterans General Hospital
Publications - 144
Citations - 5378
Bing-Wen Soong is an academic researcher from Taipei Veterans General Hospital. The author has contributed to research in topics: Spinocerebellar ataxia & Ataxia. The author has an hindex of 39, co-authored 141 publications receiving 4776 citations. Previous affiliations of Bing-Wen Soong include Taipei Medical University & National Institutes of Health.
Papers
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Journal ArticleDOI
Extensive molecular genetic survey of Taiwanese patients with amyotrophic lateral sclerosis
Bing-Wen Soong,Bing-Wen Soong,Kon Ping Lin,Kon Ping Lin,Yuh-Cherng Guo,Chou Ching K. Lin,Pei-Chien Tsai,Pei-Chien Tsai,Yi-Chu Liao,Yi-Chu Liao,Yi-Chun Lu,Shuu Jiun Wang,Ching Piao Tsai,Ching Piao Tsai,Yi-Chung Lee,Yi-Chung Lee +15 more
TL;DR: The frequency and spectrum of mutations in major ALS-causing genes in a Taiwanese ALS cohort of Han Chinese origin are determined and are indispensable for designing optimal strategies of mutational analysis and genetic counseling of ALS for patients of Chinese origin.
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Depletion of mitochondrial DNA in leukocytes of patients with poly-Q diseases.
Chin-San Liu,Wen-Ling Cheng,Shou-Jen Kuo,Jie-Yuan Li,Bing-Wen Soong,Bing-Wen Soong,Yau-Huei Wei +6 more
TL;DR: It is suggested that leukocyte mtDNA content correlates with the length of GAG repeat and may serve as an index of the severity of poly-Q diseases.
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Dysregulated brain creatine kinase is associated with hearing impairment in mouse models of Huntington disease
Yow-Sien Lin,Chiung-Mei Chen,Bing-Wen Soong,Yih-Ru Wu,Hui-Mei Chen,Wen-Ying Yeh,Dai-Rong Wu,Yi-Jun Lin,Paul Wai-Fung Poon,Mei-Ling Cheng,Chih-Hung Wang,Yijuang Chern +11 more
TL;DR: Data suggest that creatine may be useful for treating the hearing abnormalities of patients with HD, and treatment with creatine supplements ameliorated the hearing impairment of HD mice, suggesting that the impaired PCr-CK system in the cochlea ofHD mice may contribute to their hearing impairment.
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Expression of the germ cell alkaline phosphatase gene in human choriocarcinoma cells.
TL;DR: In this paper, the structures of the internal exons (II-X) of the germ cell ALP gene were determined previously based on their similarity to the placental ALP gene.
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Regional patterns of cerebral glucose metabolism in spinocerebellar ataxia type 2, 3 and 6 : a voxel-based FDG-positron emission tomography analysis.
TL;DR: While all SCAs have impaired cerebellar functions, the Cerebellar FDG metabolism was most severely compromised in SCA2, and the FDGs metabolism in the lentiform nucleus and medulla was characteristically worst inSCA3, while there was no brainstem involvement in SC a6.