B
Birgir Palsson
Researcher at deCODE genetics
Publications - 4
Citations - 425
Birgir Palsson is an academic researcher from deCODE genetics. The author has contributed to research in topics: Preeclampsia & Gene. The author has an hindex of 4, co-authored 4 publications receiving 414 citations.
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Journal ArticleDOI
A Genome-Wide Scan Reveals a Maternal Susceptibility Locus for Pre-Eclampsia on Chromosome 2p13
Reynir Arngrímsson,Sigrún Siguróaróóttir,Michael L. Frigge,Ragnheióur I. Bjarnaóóttir,Thorlakur Jonsson,Hreinn Stefansson,Ásdís Baldursdóttir,Anna S. Einarsdóttir,Birgir Palsson,Steinunn Snorradottir,A. M. A. Lachmeijer,Dan L. Nicolae,Dan L. Nicolae,Augustine Kong,Augustine Kong,Birkir Thor Bragason,Jeffrey R. Gulcher,Reynir Tómas Geirsson,Kari Stefansson +18 more
TL;DR: This work reports the results of a genome-wide screen of Icelandic families representing 343 affected women and detects a significant locus on 2p13 with a lod score of 4.70, the first reported locus for pre-eclampsia meeting the criteria for genome- wide significance.
Journal ArticleDOI
A genome-wide scan for preeclampsia in the Netherlands.
Ama Lachmeijer,Reynir Arngrímsson,EJ Bastiaans,Mike Frigge,Gerard Pals,Sigrun Sigurdardottir,Hreinn Stefansson,Birgir Palsson,Dan L. Nicolae,Dan L. Nicolae,Augustine Kong,Augustine Kong,Jan G. Aarnoudse,Gulcher,G.A. Dekker,L.P. ten Kate,Kari Stefansson +16 more
TL;DR: Results from the Dutch genome-wide scan indicate that HELLP syndrome might have a different genetic background than preeclampsia, and two peaks with suggestive evidence for linkage in the non-HELLP families are revealed.
Journal ArticleDOI
Using quality measures to facilitate allele calling in high-throughput genotyping.
Birgir Palsson,Frosti Palsson,Mark Perlin,Hakon Gudbjartsson,Kari Stefansson,Jeffrey R. Gulcher +5 more
TL;DR: The development of a parametric approach to allele call quality control that eliminates much of the time required for manual editing of the data and results in <1% miscalls is described.
Journal ArticleDOI
A genome-wide study of allelic imbalance in human testicular germ cell tumors using microsatellite markers.
Jon Thor Bergthorsson,Bjarni A. Agnarsson,Tomas Gudbjartsson,Kjartan Magnússon,Asgeir Thoroddsen,Birgir Palsson,Johannes Bjornsson,Kari Stefansson,Jeffrey R. Gulcher,Gudmundur V. Einarsson,Laufey T. Amundadottir,Rosa B. Barkardottir +11 more
TL;DR: A genome-wide study of allelic imbalance in 32 tumors, using 710 microsatellite markers, finds the highest prevalence of AI was found at 12p, in line with previous studies finding consistent gain of the region in TGCTs.