Johannes Bjornsson

TL;DR: Ovarian tumors from heterozygous carriers of the Icelandic mutation show loss of the wild-type allele, indicating that BRIP1 behaves like a classical tumor suppressor gene in ovarian cancer.

TL;DR: Chondrosarcomas are common solid malignant tumors of bone, second in incidence only to osteosarcoma, and require long follow‐up intervals for meaningful survival analysis.

TL;DR: It is concluded that genetic factors are involved in the etiology of many cancers and that these factors are in some cases shared by different cancer sites, and a significantly increased RR conferred upon mates of patients with cancer at some sites indicates that shared environment or nonrandom mating for certain risk factors also play a role in the familial clustering of cancer.

TL;DR: The findings suggest that some TSC-associated RCCs have clinical, pathological, or genetic features distinguishing them from sporadic RCC, and that the TSC tumor suppressor genes may play a specific pathogenic role in these tumors.

TL;DR: In this article, the formation of new vasa vasorum is regulated by inflammatory cells and not by arterial wall cells, raising the possibility that it represents a primary disease mechanism and not a secondary hypoxia-induced event.