S
Steinunn Snorradottir
Researcher at deCODE genetics
Publications - 7
Citations - 2765
Steinunn Snorradottir is an academic researcher from deCODE genetics. The author has contributed to research in topics: Genome-wide association study & Population. The author has an hindex of 5, co-authored 5 publications receiving 2645 citations.
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Journal ArticleDOI
A variant in CDKAL1 influences insulin response and risk of type 2 diabetes.
Valgerdur Steinthorsdottir,Gudmar Thorleifsson,Inga Reynisdottir,Rafn Benediktsson,Thorbjorg Jonsdottir,G. Bragi Walters,Unnur Styrkarsdottir,Solveig Gretarsdottir,Valur Emilsson,Shyamali Ghosh,Adam Baker,Steinunn Snorradottir,Hjordis Bjarnason,Maggie C.Y. Ng,Torben Hansen,Yu Z. Bagger,Robert L. Wilensky,Muredach P. Reilly,Adebowale Adeyemo,Yuanxiu Chen,Jie Zhou,Vilmundur Gudnason,Guanjie Chen,Hanxia Huang,Kerrie Lashley,Ayo Doumatey,Wing-Yee So,Ronald Ching-Wa Ma,Gitte Andersen,Knut Borch-Johnsen,Knut Borch-Johnsen,Knut Borch-Johnsen,Torben Jørgensen,Jana V. van Vliet-Ostaptchouk,Marten H. Hofker,Marten H. Hofker,Cisca Wijmenga,Cisca Wijmenga,Claus Christiansen,Daniel J. Rader,Charles N. Rotimi,Mark E. Gurney,Juliana C.N. Chan,Oluf Pedersen,Oluf Pedersen,Gunnar Sigurdsson,Jeffrey R. Gulcher,Unnur Thorsteinsdottir,Augustine Kong,Kari Stefansson +49 more
TL;DR: A genome-wide association study for type 2 diabetes (T2D) in Icelandic cases and controls is conducted, and it is found that a previously described variant in the transcription factor 7-like 2 gene (TCF7L2) gene conferred the most significant risk.
Journal ArticleDOI
The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm
Anna Helgadottir,Gudmar Thorleifsson,Kristinn P. Magnusson,Solveig Gretarsdottir,Valgerdur Steinthorsdottir,Andrei Manolescu,Gregory T. Jones,Gabriel J.E. Rinkel,Jan D. Blankensteijn,Antti Ronkainen,Juha Jääskeläinen,Yoshiki Kyo,Guy M. Lenk,Natzi Sakalihasan,Konstantinos Kostulas,Anders Gottsäter,Andrea Flex,Hreinn Stefansson,Torben Hansen,Gitte Andersen,Shantel Weinsheimer,Knut Borch-Johnsen,Knut Borch-Johnsen,Torben Jørgensen,Svati H. Shah,Arshed A. Quyyumi,Christopher B. Granger,Muredach P. Reilly,Harland Austin,Allan I. Levey,Viola Vaccarino,Ebba Palsdottir,G. Bragi Walters,Thorbjorg Jonsdottir,Steinunn Snorradottir,Dana Magnusdottir,Gudmundur H. Gudmundsson,Robert E. Ferrell,Sigurlaug Sveinbjörnsdóttir,Juha Hernesniemi,Juha Hernesniemi,Mika Niemelä,Raymond Limet,Karl Andersen,Gunnar Sigurdsson,Rafn Benediktsson,Eric L.G. Verhoeven,Joep A.W. Teijink,Diederick E. Grobbee,Daniel J. Rader,David A. Collier,Oluf Pedersen,Roberto Pola,Jan Hillert,Bengt Lindblad,Einar M. Valdimarsson,Hulda B Magnadottir,Cisca Wijmenga,Gerard Tromp,Annette F. Baas,Ynte M. Ruigrok,Andre M. van Rij,Helena Kuivaniemi,Janet T. Powell,Stefan E Matthiasson,Jeffrey R. Gulcher,Gudmundur Thorgeirsson,Augustine Kong,Unnur Thorsteinsdottir,Kari Stefansson +69 more
TL;DR: It is reported that rs10757278-G is associated with, in addition to CAD, abdominal aortic aneurysm (AAA) and intracranial aneurYSm, but not with T2D, and the role of this sequence variant is not confined to atherosclerotic diseases.
Journal ArticleDOI
Sequence Variant on 8q24 Confers Susceptibility to Urinary Bladder Cancer
Lambertus A. Kiemeney,Steinunn Thorlacius,Patrick Sulem,Frank Geller,Katja K H Aben,Simon N. Stacey,Julius Gudmundsson,Margret Jakobsdottir,Jon Thor Bergthorsson,Asgeir Sigurdsson,Thorarinn Blondal,J. Alfred Witjes,Sita H. Vermeulen,Christina A. Hulsbergen-van de Kaa,Dorine W. Swinkels,Martine Ploeg,Erik B. Cornel,Henk Vergunst,Thorgeir E. Thorgeirsson,Daniel F. Gudbjartsson,Sigurjon A. Gudjonsson,Gudmar Thorleifsson,Kari T. Kristinsson,Magali Mouy,Steinunn Snorradottir,Donatella Placidi,Marcello Campagna,Cecilia Arici,Kvetoslava Koppova,Eugene Gurzau,Peter Rudnai,Eliane Kellen,Silvia Polidoro,Simonetta Guarrera,Carlotta Sacerdote,Manuel Sanchez,Berta Saez,Gabriel Valdivia,Charlotta Ryk,Petra J. de Verdier,Annika Lindblom,Klaus Golka,D. Timothy Bishop,Margaret A. Knowles,Sigfus Nikulasson,Vigdis Petursdottir,Eirikur Jonsson,Gudmundur Geirsson,Baldvin Kristjansson,Jose I. Mayordomo,Gunnar Steineck,Stefano Porru,Frank Buntinx,Frank Buntinx,Maurice P. Zeegers,Maurice P. Zeegers,Tony Fletcher,Rajesh Kumar,Giuseppe Matullo,Paolo Vineis,Anne E. Kiltie,Jeffrey R. Gulcher,Unnur Thorsteinsdottir,Unnur Thorsteinsdottir,Augustine Kong,Thorunn Rafnar,Kari Stefansson,Kari Stefansson +67 more
TL;DR: No association was observed between UBC and the four 8q24 variants previously associated with prostate, colorectal and breast cancers, nor did rs9642880 associate with any of these three cancers.
Journal ArticleDOI
New sequence variants associated with bone mineral density
Unnur Styrkarsdottir,Bjarni V. Halldorsson,Bjarni V. Halldorsson,Solveig Gretarsdottir,Daniel F. Gudbjartsson,G. Bragi Walters,Thorvaldur Ingvarsson,Thorbjorg Jonsdottir,Jona Saemundsdottir,Steinunn Snorradottir,Tuan V. Nguyen,Tuan V. Nguyen,Peter Alexandersen,Jeffrey R. Gulcher,John A. Eisman,John A. Eisman,Claus Christiansen,Gunnar Sigurdsson,Augustine Kong,Unnur Thorsteinsdottir,Kari Stefansson +20 more
TL;DR: Four new genome-wide significant loci near the SOST gene at 17q21, the MARK3 gene at 14q32, the SP7 gene at 12q13 and the TNFRSF11A (RANK) gene at 18q21 are identified and nonsynonymous SNPs in the C17orf53, LRP4, ADAM19 and IBSP genes were suggestively associated with bone density.
Journal ArticleDOI
A Genome-Wide Scan Reveals a Maternal Susceptibility Locus for Pre-Eclampsia on Chromosome 2p13
Reynir Arngrímsson,Sigrún Siguróaróóttir,Michael L. Frigge,Ragnheióur I. Bjarnaóóttir,Thorlakur Jonsson,Hreinn Stefansson,Ásdís Baldursdóttir,Anna S. Einarsdóttir,Birgir Palsson,Steinunn Snorradottir,A. M. A. Lachmeijer,Dan L. Nicolae,Dan L. Nicolae,Augustine Kong,Augustine Kong,Birkir Thor Bragason,Jeffrey R. Gulcher,Reynir Tómas Geirsson,Kari Stefansson +18 more
TL;DR: This work reports the results of a genome-wide screen of Icelandic families representing 343 affected women and detects a significant locus on 2p13 with a lod score of 4.70, the first reported locus for pre-eclampsia meeting the criteria for genome- wide significance.