T
Tomas Gudbjartsson
Researcher at University of Iceland
Publications - 214
Citations - 7172
Tomas Gudbjartsson is an academic researcher from University of Iceland. The author has contributed to research in topics: Population & Retrospective cohort study. The author has an hindex of 33, co-authored 196 publications receiving 5985 citations. Previous affiliations of Tomas Gudbjartsson include Lund University & Brigham and Women's Hospital.
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Journal ArticleDOI
A variant associated with nicotine dependence, lung cancer and peripheral arterial disease.
Thorgeir E. Thorgeirsson,Frank Geller,Patrick Sulem,Thorunn Rafnar,Anna Wiste,Anna Wiste,Kristinn P. Magnusson,Andrei Manolescu,Gudmar Thorleifsson,Hreinn Stefansson,Andres Ingason,Simon N. Stacey,Jon Thor Bergthorsson,Steinunn Thorlacius,Julius Gudmundsson,Thorlakur Jonsson,Margret Jakobsdottir,Jona Saemundsdottir,Olof Birna Olafsdottir,Larus J. Gudmundsson,Gyda Bjornsdottir,Kristleifur Kristjansson,Halla Skuladottir,Helgi J Isaksson,Tomas Gudbjartsson,Gregory T. Jones,Thomas Mueller,Anders Gottsäter,Andrea Flex,Katja K.H. Aben,Femmie de Vegt,Peter F.A. Mulders,Dolores Isla,Maria Vidal,Laura Asín,Berta Saez,L. Murillo,Thorsteinn Blondal,Halldor Kolbeinsson,Jón G. Stefánsson,Ingunn Hansdottir,Valgerdur Runarsdottir,Roberto Pola,Bengt Lindblad,Andre M. van Rij,Benjamin Dieplinger,Meinhard Haltmayer,Jose I. Mayordomo,Lambertus A. Kiemeney,Stefan E Matthiasson,Hogni Oskarsson,Thorarinn Tyrfingsson,Daniel F. Gudbjartsson,Jeffrey R. Gulcher,Steinn Jonsson,Unnur Thorsteinsdottir,Unnur Thorsteinsdottir,Augustine Kong,Kari Stefansson,Kari Stefansson +59 more
TL;DR: A common variant in the nicotinic acetylcholine receptor gene cluster on chromosome 15q24 with an effect on smoking quantity, ND and the risk of two smoking-related diseases in populations of European descent is identified.
Journal ArticleDOI
Sequence variants at the TERT-CLPTM1L locus associate with many cancer types.
Thorunn Rafnar,Patrick Sulem,Simon N. Stacey,Frank Geller,Julius Gudmundsson,Asgeir Sigurdsson,Margret Jakobsdottir,Hafdis T. Helgadottir,Steinunn Thorlacius,Katja K H Aben,Thorarinn Blondal,Thorgeir E. Thorgeirsson,Gudmar Thorleifsson,Kristleifur Kristjansson,Kristin Thorisdottir,Rafn Ragnarsson,Bardur Sigurgeirsson,Halla Skuladottir,Tomas Gudbjartsson,Helgi J Isaksson,Gudmundur V. Einarsson,Kristrun R. Benediktsdottir,Bjarni A. Agnarsson,Karl Olafsson,Anna Salvarsdottir,Hjordis Bjarnason,Margret Asgeirsdottir,Kari T. Kristinsson,Sigurborg Matthiasdottir,Steinunn G Sveinsdottir,Silvia Polidoro,Veronica Höiom,Rafael Botella-Estrada,Kari Hemminki,Peter Rudnai,D. Timothy Bishop,Marcello Campagna,Eliane Kellen,Maurice P. Zeegers,Maurice P. Zeegers,Petra J. de Verdier,Ana Ferrer,Dolores Isla,Maria Vidal,Raquel Andrés,Berta Saez,Pablo Juberías,Javier Banzo,Sebastian Navarrete,Alejandro Tres,Donghui Kan,Annika Lindblom,Eugene Gurzau,Kvetoslava Koppova,Femmie de Vegt,Jack A. Schalken,Henricus F. M. van der Heijden,Hans J Smit,René A Termeer,Egbert Oosterwijk,Onno van Hooij,Eduardo Nagore,Stefano Porru,Gunnar Steineck,Gunnar Steineck,Johan Hansson,Frank Buntinx,Frank Buntinx,William J. Catalona,Giuseppe Matullo,Paolo Vineis,Anne E. Kiltie,Jose I. Mayordomo,Rajesh Kumar,Lambertus A. Kiemeney,Michael L. Frigge,Thorvaldur Jonsson,Hafsteinn Saemundsson,Rosa B. Barkardottir,Eirikur Jonsson,Steinn Jonsson,Jón Ólafsson,Jeffrey R. Gulcher,Gisli Masson,Daniel F. Gudbjartsson,Augustine Kong,Unnur Thorsteinsdottir,Unnur Thorsteinsdottir,Kari Stefansson,Kari Stefansson +89 more
TL;DR: It is found that rs401681[C] on chromosome 5p15 satisfied the threshold for genome-wide significance and seems to confer protection against cutaneous melanoma, and investigation of the region led to rs2736098[A], which showed stronger association with some cancer types, but neither variant could fully account for the association of the other.
Journal ArticleDOI
Tracheobronchial transplantation with a stem-cell-seeded bioartificial nanocomposite: a proof-of-concept study.
Philipp Jungebluth,Philipp Jungebluth,Evren Alici,Silvia Baiguera,Pontus Blomberg,Béla Bozóky,Claire Crowley,Oskar Einarsson,Tomas Gudbjartsson,Sylvie Le Guyader,Gert Henriksson,Ola Hermanson,Jan Erik Juto,Bertil Leidner,Bertil Leidner,Tobias Lilja,Jan Liska,Tom Luedde,Vanessa Lundin,Guido Moll,Christoph Roderburg,Staffan Strömblad,Tolga Sutlu,Emma Watz,Emma Watz,Alexander M. Seifalian,Paolo Macchiarini,Paolo Macchiarini +27 more
TL;DR: These findings, together with increased levels of regenerative-associated plasma factors, strongly suggest stem-cell homing and cell-mediated wound repair, extracellular matrix remodelling, and neovascularisation of the graft are key factors for successful clinical outcome.
Journal ArticleDOI
2017 EACTS Guidelines on perioperative medication in adult cardiac surgery.
Miguel Sousa-Uva,Stuart J. Head,Milan Milojevic,Jean-Philippe Collet,Giovanni Landoni,Manuel Castellá,Joel Dunning,Tomas Gudbjartsson,Nick J Linker,Elena Sandoval,Matthias Thielmann,Anders Jeppsson,Ulf Landmesser +12 more
TL;DR: Authors/Task Force Members: Miguel Sousa-Uva* (Chairperson) (Portugal), Stuart J. Head (Netherlands), Milan Milojevic (N Netherlands), Jean-Philippe Collet (France), Giovanni Landoni (Italy), Manuel Castella (Spain), Joel Dunning (UK), T omas Gudbjartsson (Iceland).
Journal ArticleDOI
P2 Receptor Expression Profiles in Human Vascular Smooth Muscle and Endothelial Cells.
Lingwei Wang,Lena Karlsson,Sara Moses,Anna Hultgårdh-Nilsson,Maria Andersson,Catharina Borna,Tomas Gudbjartsson,Sverker Jern,David Erlinge +8 more
TL;DR: P2X1, P2y2, and P2Y6 are the most expressed P2 receptors in SMC and are thus probably mediating the contractile and mitogenic actions of extracellular nucleotides, and are most likely mediating release of nitric oxide, endothelium-dependent hyperpolarizing factor (EDHF), and t-PA induced by extrace cellular nucleotide.