B
Birgit Liss
Researcher at University of Ulm
Publications - 78
Citations - 7192
Birgit Liss is an academic researcher from University of Ulm. The author has contributed to research in topics: Substantia nigra & Dopamine. The author has an hindex of 39, co-authored 75 publications receiving 6406 citations. Previous affiliations of Birgit Liss include University of Marburg & University of Oxford.
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Journal ArticleDOI
Hereditary parkinsonism with dementia is caused by mutations in ATP13A2, encoding a lysosomal type 5 P-type ATPase.
Alfredo Ramirez,André Heimbach,Jan Gründemann,Barbara Stiller,Daniel J. Hampshire,L. Pablo Cid,Ingrid Goebel,Ammar F. Mubaidin,Abdul-Latif Wriekat,Jochen Roeper,Amir S. Najim Al-Din,Axel M. Hillmer,Meliha Karsak,Birgit Liss,C. Geoffrey Woods,Maria I. Behrens,Christian Kubisch +16 more
TL;DR: Loss-of-function mutations in a previously uncharacterized, predominantly neuronal P-type ATPase gene, ATP13A2, underlying an autosomal recessive form of early-onset parkinsonism with pyramidal degeneration and dementia are described.
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Unique Properties of Mesoprefrontal Neurons within a Dual Mesocorticolimbic Dopamine System
TL;DR: A type of dopaminergic neuron within the mesocorticolimbic dopamine system with unconventional fast-firing properties and small DAT/TH mRNA expression ratios that selectively projects to prefrontal cortex and nucleus accumbens core and medial shell as well as to basolateral amygdala is identified.
Journal ArticleDOI
ATP-sensitive K+ channels in the hypothalamus are essential for the maintenance of glucose homeostasis.
Takashi Miki,Birgit Liss,Kohtaro Minami,Tetsuya Shiuchi,Atsunori Saraya,Yasushige Kashima,Masatsugu Horiuchi,Frances M. Ashcroft,Yasuhiko Minokoshi,Jochen Roeper,Susumu Seino +10 more
TL;DR: It is demonstrated that KATP channels are important in glucose sensing in VMH GR neurons, and are essential for the maintenance of glucose homeostasis.
Journal ArticleDOI
Ih Channels Contribute to the Different Functional Properties of Identified Dopaminergic Subpopulations in the Midbrain
TL;DR: Diversity within the DA system is not restricted to distinct axonal projections and differences in synaptic connectivity, but also involves differences in postsynaptic conductances between neurochemically and topographically distinct DA neurons.
Journal ArticleDOI
K-ATP channels promote the differential degeneration of dopaminergic midbrain neurons
Birgit Liss,Birgit Liss,Olga Haeckel,Johannes Wildmann,Takashi Miki,Susumu Seino,Jochen Roeper,Jochen Roeper +7 more
TL;DR: It is shown that in response to parkinsonism-inducing toxins, electrophysiological activity of SN neurons, but not VTA DA neurons, is lost owing to activation of K-ATP channels.