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Blake Borgeson
Researcher at University of Texas at Austin
Publications - 14
Citations - 1205
Blake Borgeson is an academic researcher from University of Texas at Austin. The author has contributed to research in topics: Centriolar satellite & Null distribution. The author has an hindex of 8, co-authored 14 publications receiving 866 citations. Previous affiliations of Blake Borgeson include University of Toronto & University of Bern.
Papers
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Journal ArticleDOI
Cell Painting, a high-content image-based assay for morphological profiling using multiplexed fluorescent dyes
Mark-Anthony Bray,Shantanu Singh,Han Han,Chadwick T. Davis,Blake Borgeson,Cathy L Hartland,Maria Kost-Alimova,Sigrun M. Gustafsdottir,Christopher C. Gibson,Anne E. Carpenter +9 more
TL;DR: This protocol describes the design and execution of experiments using Cell Painting, which is a morphological profiling assay that multiplexes six fluorescent dyes, imaged in five channels, to reveal eight broadly relevant cellular components or organelles.
Journal ArticleDOI
Panorama of ancient metazoan macromolecular complexes
Cuihong Wan,Cuihong Wan,Blake Borgeson,Sadhna Phanse,Fan Tu,Kevin Drew,Greg W. Clark,Xuejian Xiong,Olga Kagan,Julian Kwan,Alexandr Bezginov,Kyle Chessman,Swati Pal,Graham L. Cromar,Ophelia Papoulas,Zuyao Ni,Daniel R. Boutz,Snejana Stoilova,Pierre C. Havugimana,Xinghua Guo,Ramy H. Malty,Mihail Sarov,Jack Greenblatt,Mohan Babu,W. Brent Derry,Elisabeth R. M. Tillier,John B. Wallingford,John Parkinson,Edward M. Marcotte,Andrew Emili +29 more
TL;DR: A draft conservation map is generated consisting of more than one million putative high-confidence co-complex interactions for species with fully sequenced genomes that encompasses functional modules present broadly across all extant animals.
Journal ArticleDOI
Integration of over 9,000 mass spectrometry experiments builds a global map of human protein complexes.
Kevin Drew,Chaehee Lee,Ryan L. Huizar,Fan Tu,Blake Borgeson,Claire D. McWhite,Yun Ma,Yun Ma,John B. Wallingford,Edward M. Marcotte +9 more
TL;DR: This work presents hu.MAP, the most comprehensive and accurate human protein complex map to date, containing > 4,600 total complexes, > 7,700 proteins, and > 56,000 unique interactions, including thousands of confident protein interactions not identified by the original publications.
Patent
Determining Viewing Distance Information for an Image
Blake Borgeson,Orion Seth Jensen +1 more
TL;DR: In this article, a method for enabling a user to interactively design a sign to be manufactured is presented, where the user can specify various criteria for the sign, such as sign size, image/text size, etc.
Journal ArticleDOI
Improved targeting device and computer navigation for accurate placement of brachytherapy needles.
TL;DR: An image-based planning and navigation system for brachytherapy that includes a custom-made mechanical positioning arm that allows rough and fine adjustment of the needle position and shows that the proposed procedure provides a promising tool for the safe treatment of tumors in the skull base area.