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Bo Kyoung Yeo
Researcher at Daegu Gyeongbuk Institute of Science and Technology
Publications - 37
Citations - 159
Bo Kyoung Yeo is an academic researcher from Daegu Gyeongbuk Institute of Science and Technology. The author has contributed to research in topics: Large Hadron Collider & Standard Model (mathematical formulation). The author has an hindex of 4, co-authored 5 publications receiving 77 citations.
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Journal ArticleDOI
Autophagic death of neural stem cells mediates chronic stress-induced decline of adult hippocampal neurogenesis and cognitive deficits.
Seonghee Jung,Seongwon Choe,Hanwoong Woo,Hyeonjeong Jeong,Hyun Kyu An,Hyewon Moon,Hye Young Ryu,Bo Kyoung Yeo,Ye Won Lee,Hyosun Choi,Ji Young Mun,Woong Sun,Han Kyoung Choe,Eun Kyoung Kim,Seong-Woon Yu +14 more
TL;DR: It is shown that chronic restraint stress suppresses adult hippocampal neurogenesis in mice by inducing autophagic cell death (ACD) of hippocampal neural stem cells (NSCs) through SGK3 (serum/glucocorticoid regulated kinase 3) without signs of apoptosis.
Journal ArticleDOI
Valosin-containing protein is a key mediator between autophagic cell death and apoptosis in adult hippocampal neural stem cells following insulin withdrawal
Bo Kyoung Yeo,Caroline Jeeyeon Hong,Kyung Min Chung,Hanwoong Woo,Kyungchan Kim,Seonghee Jung,Eun Kyoung Kim,Seong-Woon Yu +7 more
TL;DR: This first report on the role of VCP in regulation of NSC cell death demonstrates that VCP may play an essential role in the initiation of autophagy and mediation of crosstalk between ACD and apoptosis in HCN cells whenAutophagy level is high upon insulin withdrawal.
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GSK3B induces autophagy by phosphorylating ULK1
Hye Young Ryu,Leah Eunjung Kim,Hyeonjeong Jeong,Bo Kyoung Yeo,Ji-Won Lee,Hyeri Nam,Shinwon Ha,Hyun-Kyu An,Hyunhee Park,Seonghee Jung,Kyung Min Chung,Jiyea Kim,Byung-Hoon Lee,Heesun Cheong,Eun Kyoung Kim,Seong-Woon Yu +15 more
TL;DR: Following insulin withdrawal, GSK3B directly interacted with and activated ULK1 via phosphorylation of S405 and S415 within the GABARAP-interacting region, revealing the importance of G SK3B-mediated phosphorylated for ULK 1 regulation and autophagy induction and potentially for tumorigenesis.
Journal ArticleDOI
Valosin-containing protein (VCP): structure, functions, and implications in neurodegenerative diseases
Bo Kyoung Yeo,Seong-Woon Yu +1 more
TL;DR: The structure and cellular functions of VCP are summarized, especially focusing on apoptosis and two major cellular degradation pathways, the ubiquitin–proteasome system and autophagy.
Journal ArticleDOI
Fas-apoptotic inhibitory molecule 2 localizes to the lysosome and facilitates autophagosome-lysosome fusion through the LC3 interaction region motif–dependent interaction with LC3
Caroline Jeeyeon Hong,Jihye Yeon,Bo Kyoung Yeo,Hanwoong Woo,Hyun-Kyu An,Woojung Heo,Kyuhyung Kim,Seong-Woon Yu +7 more
TL;DR: It is shown that FAIM2 localizes to the lysosomes at basal state and facilitates autophagy through interaction with microtubule‐associated protein 1 light chain 3 proteins in human neuroblastoma SH‐SY5Y cells.