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Bo Xu
Researcher at Tianjin Medical University Cancer Institute and Hospital
Publications - 86
Citations - 6977
Bo Xu is an academic researcher from Tianjin Medical University Cancer Institute and Hospital. The author has contributed to research in topics: DNA damage & DNA repair. The author has an hindex of 30, co-authored 77 publications receiving 5809 citations. Previous affiliations of Bo Xu include Capital Normal University & LSU Health Sciences Center New Orleans.
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A deep learning algorithm using CT images to screen for Corona Virus Disease (COVID-19)
Shuai Wang,Bo Kang,Jinlu Ma,Xianjun Zeng,Mingming Xiao,Jia Guo,Mengjiao Cai,Jingyi Yang,Yaodong Li,Xiangfei Meng,Bo Xu +10 more
TL;DR: The results demonstrate the proof-of-principle for using artificial intelligence to extract radiological features for timely and accurate COVID-19 diagnosis.
Journal ArticleDOI
ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway
Dae-Sik Lim,Seong-Tae Kim,Bo Xu,Richard S. Maser,Junyu Lin,John H.J. Petrini,Michael B. Kastan +6 more
TL;DR: Observations link ATM and p95/nbs1 in a common signalling pathway and provide an explanation for phenotypic similarities in these two diseases.
Journal ArticleDOI
Involvement of Brca1 in S-phase and G(2)-phase checkpoints after ionizing irradiation.
TL;DR: The results clarify the checkpoint roles for each of these three gene products, demonstrate that control of cell cycle arrests must now be included among the important functions of Brca1 in cellular responses to DNA damage, and suggest that Atm phosphorylation of BrCA1 is required for the G2/M checkpoint.
Journal ArticleDOI
A deep learning algorithm using CT images to screen for Corona virus disease (COVID-19).
Shuai Wang,Bo Kang,Jinlu Ma,Xianjun Zeng,Mingming Xiao,Jia Guo,Mengjiao Cai,Jingyi Yang,Yaodong Li,Xiangfei Meng,Bo Xu,Bo Xu +11 more
TL;DR: In this article, a deep learning algorithm was used to detect the presence of COVID-19 in CT images during the 2015-2016 influenza season, achieving an accuracy of 89.5% with a specificity of 0.88 and sensitivity of 0.87.
Journal ArticleDOI
Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage
TL;DR: It is shown that the protein kinase, Atm, which belongs to a family of phosphatidylinositol 3-kinases that regulate cell cycle checkpoints and DNA recombination and repair, phosphorylates Smc1 protein after ionizing irradiation.