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Bo Yang
Researcher at Rensselaer Polytechnic Institute
Publications - 52
Citations - 1672
Bo Yang is an academic researcher from Rensselaer Polytechnic Institute. The author has contributed to research in topics: Heparin & Heparan sulfate. The author has an hindex of 25, co-authored 52 publications receiving 1492 citations. Previous affiliations of Bo Yang include Ocean University of China & Harvard University.
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Mechanism of mild acid hydrolysis of galactan polysaccharides with highly ordered disaccharide repeats leading to a complete series of exclusively odd-numbered oligosaccharides.
TL;DR: The identification, by various MS and chromatographic techniques, of an unexpected series of exclusively odd‐numbered oligosaccharide fragments from its hydrolytic products, which were derived from two‐step cleavages of the glycosidic bonds on either sides of the 3,6‐anhydrogalactose residues.
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Analysis of glycosaminoglycan-derived, precolumn, 2-aminoacridone–labeled disaccharides with LC-fluorescence and LC-MS detection
TL;DR: HPPLC with on-line electrospray ionization mass spectrometry (ESI-MS) offers a relatively soft ionization method for detection and characterization of sulfated oligosaccharides, providing one of the most practical and quantitative approaches for compositional mapping.
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Disaccharide analysis of glycosaminoglycan mixtures by ultra-high-performance liquid chromatography–mass spectrometry
TL;DR: Quantitative disaccharide compositional analysis was successfully applied to cell, tissue, and biological fluid samples for the picomole level detection of glycosaminoglycan composition and structure.
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Structural Characterization of Pharmaceutical Heparins Prepared from Different Animal Tissues
Li Fu,Guoyun Li,Guoyun Li,Bo Yang,Akihiro Onishi,Lingyun Li,Peilong Sun,Fuming Zhang,Robert J. Linhardt +8 more
TL;DR: Three heparins from porcine, ovine, and bovine were characterized through state-of-the-art carbohydrate analysis methods with a view profiling their physicochemical properties and some insight is provided into the variability of heparin obtained from these three species.
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Ultra-performance ion-pairing liquid chromatography with on-line electrospray ion trap mass spectrometry for heparin disaccharide analysis.
Bo Yang,Amanda Weyers,Jong Youn Baik,Jong Youn Baik,Eric Sterner,Susan T. Sharfstein,Shaker A. Mousa,Fuming Zhang,Jonathan S. Dordick,Robert J. Linhardt +9 more
TL;DR: A high-resolution method for the separation and analysis of disaccharides prepared from heparin and heparan sulfate (HS) usingHeparin lyases is described, which provides high sensitivity without being subject to interference from proteins, peptides, and other sample impurities.