Bradford S. Schwartz

TL;DR: The membrane has long been viewed as an inert cellophane-like membrane that lines the circulatory system with its primary essential function being the maintenance of vessel wall permeability.

TL;DR: It is shown that u-PA in its single-chain form exhibits a reactive active site serine, and the enzymatic activity of this molecule is augmented 100-fold upon binding to the u- PA receptor on monocytes as compared with the enzyme activity of the same number of molecules in the fluid phase, likely an important mechanism for the initiation and control of cell surface-associated fibrinolysis.

TL;DR: Epsilon-aminocaproic acid is a safe and effective therapy for those patients with acute promyelocytic leukemia who develop coagulopathy associated with low levels of alpha-2-plasmin inhibitor.

TL;DR: The binding of scuPA to cellular and to recombinant soluble urokinase-type plasminogen activator receptors (suPAR) increases its catalytic activity as measured by the cleavage of a uro Kinase-specific chromogenic substrate, suggesting that scu PA may undergo a reversible transformation between a latent and an active state.

TL;DR: Evaluation of four onion genotypes grown in a field study at four US locations in 1994 demonstrated onions with mild flavor and low sulfur content exhibited significantly lower antiplatelet activity than those containing high levels of sulfur, demonstrating antiplatelets activity is genotype dependent and correlated with bulb sulfur content.