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Brent T. Tan
Researcher at Stanford University
Publications - 21
Citations - 1128
Brent T. Tan is an academic researcher from Stanford University. The author has contributed to research in topics: Medicine & Lymphoma. The author has an hindex of 7, co-authored 16 publications receiving 924 citations.
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Journal ArticleDOI
Anti-CD47 Antibody Synergizes with Rituximab to Promote Phagocytosis and Eradicate Non-Hodgkin Lymphoma
Mark P. Chao,Ash A. Alizadeh,Chad Tang,June Helen Myklebust,June Helen Myklebust,Bindu Varghese,Saar Gill,Max Jan,Adriel C. Cha,Charles Chan,Brent T. Tan,Christopher Y. Park,Feifei Zhao,Holbrook E Kohrt,Raquel Malumbres,Javier Briones,Randy D. Gascoyne,Izidore S. Lossos,Ronald Levy,Irving L. Weissman,Ravindra Majeti +20 more
TL;DR: The eradication of human NHL solely with a monoclonal antibody therapy combining rituximab with a blocking anti-CD47 antibody, which synergized through a mechanism combining Fc receptor (FcR)-dependent and FcR-independent stimulation of phagocytosis that might be applicable to many other cancers.
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The Wilms' tumor gene WT1-GFP knock-in mouse reveals the dynamic regulation of WT1 expression in normal and leukemic hematopoiesis.
Naoki Hosen,Toshiaki Shirakata,Sumiyuki Nishida,Masashi Yanagihara,Akio Tsuboi,Manabu Kawakami,Yusuke Oji,Yoshihiro Oka,Masaru Okabe,Brent T. Tan,Haruo Sugiyama,Irving L. Weissman +11 more
TL;DR: The results demonstrate that the WT1GFP/+ mouse is a powerful tool for analyzing WT1-expressing cells, and they highlight the potential of WT1, as a specific therapeutic target that is expressed in LSCs but not in normal HSCs.
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Evaluation of the Beckman Coulter UniCel DxH 800, Beckman Coulter LH 780, and Abbott Diagnostics Cell-Dyn Sapphire Hematology Analyzers on Adult Specimens in a Tertiary Care Hospital
TL;DR: In the instrument vs 400-cell manual differential comparison, all 3 instruments showed similar and acceptable accuracy to the reference method except for nucleated RBC (NRBC) enumeration, in which the DxH 800 and Sapphire outperformed the LH 780.
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The Frequency of Immunoglobulin Heavy Chain Gene and T-Cell Receptor γ-Chain Gene Rearrangements and Epstein-Barr Virus in ALK+ and ALK− Anaplastic Large Cell Lymphoma and Other Peripheral T-Cell Lymphomas
TL;DR: It is demonstrated that, in the absence of an associated B-cell proliferation, IGH clonality occurs infrequently (8%) in specific PTCL subtypes.
Journal ArticleDOI
Primary lymphoma of bone in the pediatric and young adult population
Karen M. Chisholm,Robert S. Ohgami,Brent T. Tan,Robert P. Hasserjian,Olga K. Weinberg,Olga K. Weinberg +5 more
TL;DR: This largest pediatric series of PLB identifies DLBCL as the most frequent subtype and documents rarer occurrences of BLL, ALCL, and follicular lymphomas.