Raquel Malumbres

TL;DR: The results suggest that miRNA expression profile could have relevance to the biological and clinical behavior of colorectal neoplasia and the expression level of miR-31 was correlated with the stage of CRC tumor.

TL;DR: The eradication of human NHL solely with a monoclonal antibody therapy combining rituximab with a blocking anti-CD47 antibody, which synergized through a mechanism combining Fc receptor (FcR)-dependent and FcR-independent stimulation of phagocytosis that might be applicable to many other cancers.

TL;DR: Although an important component of the biology of a malignant cell is inherited from its nontransformed cellular progenitor-GC centroblasts-aberrant miRNA expression is acquired upon cell transformation, expression of some of the miRNAs in this signature is correlated with clinical outcome of uniformly treated DLBCL patients.

TL;DR: The expression of specific miRNAs may be useful for DLBCL survival prediction and their role in the pathogenesis of this disease should be examined further.

TL;DR: It is shown that PTP1B expression may be preferentially elevated in activated B cell-like diffuse large B-cell lymphomas and a novel regulatory loop for the regulation of IL-4-induced STAT6 signaling is delineated that may have important implications in both neoplastic and inflammatory processes.