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Brett E. Bouma
Researcher at Harvard University
Publications - 496
Citations - 52032
Brett E. Bouma is an academic researcher from Harvard University. The author has contributed to research in topics: Optical coherence tomography & Laser. The author has an hindex of 116, co-authored 474 publications receiving 49561 citations. Previous affiliations of Brett E. Bouma include Hope College & Lahey Hospital & Medical Center.
Papers
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Journal ArticleDOI
Characterization of Atherosclerotic Plaques by Laser Speckle Imaging
Seemantini K. Nadkarni,Brett E. Bouma,Tina Helg,Raymond Chan,Elkan F. Halpern,Alexandra H. Chau,Milan Singh Minsky,Jason T. Motz,S. L. Houser,Guillermo J. Tearney +9 more
TL;DR: The results demonstrate that LSI is a highly sensitive technique for characterizing plaque and identifying thin-cap fibroatheromas and provide an index of plaque viscoelasticity and facilitates the characterization of plaque type.
Patent
Method and apparatus for three-dimensional spectrally encoded imaging
TL;DR: In this article, a method and apparatus for obtaining three-dimensional surface measurements using phase-sensitive spectrally encoded imaging is described, where both transverse and depth information is transmitted through a singlemode optical fiber, allowing this technique to be incorporated into a miniature probe.
Journal ArticleDOI
Optical coherence tomography for imaging the vulnerable plaque
TL;DR: Results show that intracoronary OCT may be safely conducted in patients and that it provides abundant information regarding plaque microscopic morphology, which is essential to the identification and study of high-risk lesions.
Journal ArticleDOI
Two-axis magnetically-driven MEMS scanning catheter for endoscopic high-speed optical coherence tomography
Ki Hean Kim,B. Hyle Park,Gopi N. Maguluri,Tommy W. Lee,Fran J. Rogomentich,Mirela G. Bancu,Brett E. Bouma,Johannes F. de Boer,Jonathan J. Bernstein +8 more
TL;DR: A two-axis scanning catheter was developed for 3D endoscopic imaging with spectral domain optical coherence tomography (SD-OCT) with microelectromechanical systems (MEMS) technology and both intensity and polarization-sensitive images could be acquired simultaneously at 18.5K axial scans/s.
Journal ArticleDOI
Speckle reduction in OCT using massively-parallel detection and frequency-domain ranging
TL;DR: Incoherent averaging of the angle-resolved data is shown to yield substantial speckle reduction (as high as an 8 dB SNR improvement) in images of a tissue phantom and esophageal tissue ex vivo.