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Brett E. Bouma
Researcher at Harvard University
Publications - 496
Citations - 52032
Brett E. Bouma is an academic researcher from Harvard University. The author has contributed to research in topics: Optical coherence tomography & Laser. The author has an hindex of 116, co-authored 474 publications receiving 49561 citations. Previous affiliations of Brett E. Bouma include Hope College & Lahey Hospital & Medical Center.
Papers
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Journal ArticleDOI
Complex differential variance angiography with noise-bias correction for optical coherence tomography of the retina.
TL;DR: The noise-bias correction improved the CDV imaging of the blood flow in tissue layers with a low signal-to-noise ratio and suppressed false indications of blood flow outside the tissue.
Journal Article
Ultra-high speed and ultra-high resolution spectral-domain optical coherence tomography and optical Doppler tomography in ophthalmology.
Barry Cense,Teresa C. Chen,Nader Nassif,Mark C. Pierce,Seok Hyun Yun,Boris Hyle Park,Brett E. Bouma,Guillermo J. Tearney,J. F. de Boer +8 more
TL;DR: Ultra-high resolution optical coherence tomography structural intensity and optical Doppler tomography flow velocity images of the human retina in vivo are presented, showing pulsatile flow in retinal arteries and veins.
Patent
System and method providing intracoronary laser speckle imaging for the detection of vulnerable plaque
TL;DR: In this article, a wave-guiding arrangement was proposed to reduce the crosstalk between two wave-guide arrangements associated with one another that are configured to receive a further electro-magnetic radiation reflected from the tissue and transmit at least one speckle pattern associated with the further EM radiation.
Journal ArticleDOI
An automated image processing method to quantify collagen fibre organization within cutaneous scar tissue.
Kyle P. Quinn,Alexander Golberg,Alexander Golberg,G. Felix Broelsch,Saiqa Khan,Martin Villiger,Brett E. Bouma,William G. Austen,Robert L. Sheridan,Martin C. Mihm,Martin L. Yarmush,Martin L. Yarmush,Irene Georgakoudi +12 more
TL;DR: An image analysis technique for the rapid quantification of fibre alignment at each pixel location is evaluated for quantitatively mapping scar formation in histological sections of cutaneous burns to provide objective surrogate endpoints for evaluating cutaneous wound repair and regeneration.
Journal ArticleDOI
Reflectance confocal microscopy for the diagnosis of eosinophilic esophagitis: a pilot study conducted on biopsy specimens
Hongki Yoo,Dongkyun Kang,Aubrey J. Katz,Gregory Y. Lauwers,Norman S. Nishioka,Yukako Yagi,Pornthep Tanpowpong,Jacqueline Namati,Brett E. Bouma,Brett E. Bouma,Guillermo J. Tearney,Guillermo J. Tearney +11 more
TL;DR: It is demonstrated that RCM can be used to accurately count intraepithelial eosinophils and identify other microscopic abnormalities associated with EoE on freshly excised biopsy samples, and suggest thatRCM may be developed into a tool for assessing eos inophilic infiltration in the esophagus in vivo.