B
Brett M. Barney
Researcher at University of Minnesota
Publications - 54
Citations - 2580
Brett M. Barney is an academic researcher from University of Minnesota. The author has contributed to research in topics: Nitrogenase & Azotobacter vinelandii. The author has an hindex of 30, co-authored 51 publications receiving 2227 citations. Previous affiliations of Brett M. Barney include Virginia Tech & Arizona State University.
Papers
More filters
Journal ArticleDOI
Substrate interaction at an iron-sulfur face of the FeMo-cofactor during nitrogenase catalysis.
TL;DR: Evidence is provided to indicate that the smaller alkyne substrate acetylene (HC≡CH), the physiological substrate dinitrogen, and its semi-reduced form hydrazine (H2N-NH2) interact with the same Fe-S face of the FeMo-cofactor.
Journal ArticleDOI
Breaking the N2 triple bond : insights into the nitrogenase mechanism
Brett M. Barney,Hong-In Lee,Patricia C. Dos Santos,Brian M. Hoffman,Dennis R. Dean,Lance C. Seefeldt +5 more
TL;DR: A comparison of the current state of knowledge of the trapped species arising from non-physiological substrates and nitrogenous substrates is beginning to reveal some of the intricacies of how nitrogenase breaks the N2 triple bond.
Journal ArticleDOI
Characterization of a fatty acyl-CoA reductase from Marinobacter aquaeolei VT8: a bacterial enzyme catalyzing the reduction of fatty acyl-CoA to fatty alcohol.
TL;DR: A novel bacterial enzyme from Marinobacter aquaeolei VT8 is identified, purify, and characterize that catalyzes the reduction of fatty acyl-CoA by four electrons to the corresponding fatty alcohol, eliminating the need for a separate fatty aldehyde reductase.
Journal ArticleDOI
The Electron Bifurcating FixABCX Protein Complex from Azotobacter vinelandii: Generation of Low-Potential Reducing Equivalents for Nitrogenase Catalysis.
Rhesa N. Ledbetter,Amaya M. Garcia Costas,Carolyn E. Lubner,David W. Mulder,Monika Tokmina-Lukaszewska,Jacob H. Artz,Angela Patterson,Timothy S. Magnuson,Zackary J. Jay,H. Diessel Duan,Jacquelyn Miller,Mary H. Plunkett,John P. Hoben,Brett M. Barney,Ross P. Carlson,Anne-Frances Miller,Brian Bothner,Paul W. King,John W. Peters,John W. Peters,Lance C. Seefeldt +20 more
TL;DR: This study informs a mechanism for electron bifurcation, offering insight into a unique method for delivery of low-potential electrons required for energy-intensive biochemical conversions.
Journal ArticleDOI
Intermediates Trapped during Nitrogenase Reduction of N⋮N, CH3−NNH, and H2N−NH2
Brett M. Barney,Tran Chin Yang,Robert Y. Igarashi,Patricia C. Dos Santos,Mikhail Laryukhin,Hong-In Lee,Hong-In Lee,Brian M. Hoffman,Dennis R. Dean,Lance C. Seefeldt +9 more
TL;DR: In this paper, a high population intermediate has been trapped on the nitrogenase active site FeMo cofactor during reduction of N2 and intermediates have been trapped during CH3−NNH by the α-195Gln variant.