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Brian C. Gilmour
Publications - 4
Citations - 198
Brian C. Gilmour is an academic researcher. The author has contributed to research in topics: Extended family & Pattern recognition receptor. The author has an hindex of 2, co-authored 3 publications receiving 37 citations.
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Journal ArticleDOI
A research agenda for ageing in China in the 21st century (2nd edition): Focusing on basic and translational research, long-term care, policy and social networks
Evandro Fei Fang,Chenglong Xie,Chenglong Xie,Joseph Adam Schenkel,Chenkai Wu,Qian Long,Honghua Cui,Yahyah Aman,Johannes Frank,Jing Liao,Huachun Zou,Huachun Zou,Ninie Y. Wang,Jing Wu,Xiaoting Liu,Li Tao,Fang Yuan,Zhangming Niu,Guang Yang,Jiangshui Hong,Qian Wang,Guobing Chen,Jun Li,Hou-Zao Chen,Lin Kang,Huanxing Su,Brian C. Gilmour,Xinqiang Zhu,Hong Jiang,Na He,Tao Jun,Sean Xiao Leng,Tanjun Tong,Jean Woo +33 more
TL;DR: Collectively, synergies across disciplines on policies, geriatric care, drug development, personal awareness, the use of big data, machine learning and personalized medicine will transform China into a country that enables the most for its elderly, maximizing and celebrating their longevity in the coming decades.
Journal ArticleDOI
Targeting NAD+ in translational research to relieve diseases and conditions of metabolic stress and ageing.
Brian C. Gilmour,Ruben Gudmundsrud,Johannes Frank,Amund Hov,Sofie Lautrup,Yahyah Aman,Helge Røsjø,Charles Brenner,Mathias Ziegler,Ole-Bjørn Tysnes,Charalampos Tzoulis,Torbjørn Omland,Arne Søraas,Trygve Holmøy,Linda H. Bergersen,Jon Storm-Mathisen,Hilde Nilsen,Evandro Fei Fang +17 more
TL;DR: A consensus is emerging with respect to the design of clinical trials in order to measure meaningful parameters and ensure safety, as well as other potential NR-based clinical trials.
Journal ArticleDOI
Crosstalk among DNA Damage, Mitochondrial Dysfunction, Impaired Mitophagy, Stem Cell Attrition, and Senescence in the Accelerated Ageing Disorder Werner Syndrome.
Ruben Gudmundsrud,Tarjei H. Skjånes,Brian C. Gilmour,Domenica Caponio,Sofie Lautrup,Evandro Fei Fang +5 more
TL;DR: Werner syndrome (WS) is an accelerated ageing disease caused by multiple mutations in the gene encoding the Werner DNA helicase (WRN), and the major clinical features of WS include wrinkles, grey hair, osteoporosis, and metabolic phenomena such as atherosclerosis, diabetes, and fatty liver, but occur earlier, in middle age as discussed by the authors.
Posted ContentDOI
RNA-sensing pattern-recognition receptors synergize with TLR2 or dectin-1 to trigger high production of IL-12p70 by human dendritic cells
TL;DR: Six different combinations of PRR ligands able to induce high IL-12p70 production by human DCs are identified and may represent strong adjuvant candidates in particular for therapeutic cancer vaccines.